ID U2BCZ8_9PSED Unreviewed; 1213 AA.
AC U2BCZ8;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Urea carboxylase {ECO:0000313|EMBL:ERI53091.1};
GN ORFNames=N878_00525 {ECO:0000313|EMBL:ERI53091.1};
OS Pseudomonas sp. EGD-AK9.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1386078 {ECO:0000313|EMBL:ERI53091.1, ECO:0000313|Proteomes:UP000016488};
RN [1] {ECO:0000313|EMBL:ERI53091.1, ECO:0000313|Proteomes:UP000016488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EGD-Ak9 {ECO:0000313|Proteomes:UP000016488};
RA Kapley A., Sagarkar S., Bhardwaj P., Qureshi A., Khardenavis A.,
RA Purohit H.J.;
RT "Indian agricultural soil isolates capable of pesticide degradation.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=biotin; Xref=ChEBI:CHEBI:57586;
CC Evidence={ECO:0000256|ARBA:ARBA00001953};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERI53091.1}.
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DR EMBL; AVOF01000129; ERI53091.1; -; Genomic_DNA.
DR RefSeq; WP_021442973.1; NZ_AVOF01000129.1.
DR AlphaFoldDB; U2BCZ8; -.
DR PATRIC; fig|1386078.3.peg.1352; -.
DR OrthoDB; 9763189at2; -.
DR Proteomes; UP000016488; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.30.1360.40; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 2.40.100.10; Cyclophilin-like; 2.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR005481; BC-like_N.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR003778; CT_A_B.
DR InterPro; IPR003833; CT_C_D.
DR InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR InterPro; IPR011053; Single_hybrid_motif.
DR InterPro; IPR014084; Urea_COase.
DR NCBIfam; TIGR00724; urea_amlyse_rel; 1.
DR NCBIfam; TIGR02712; urea_carbox; 1.
DR PANTHER; PTHR18866; CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE; 1.
DR PANTHER; PTHR18866:SF33; METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00289; Biotin_carb_N; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR Pfam; PF02626; CT_A_B; 1.
DR Pfam; PF02682; CT_C_D; 1.
DR SMART; SM00796; AHS1; 1.
DR SMART; SM00797; AHS2; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF50891; Cyclophilin-like; 2.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF160467; PH0987 N-terminal domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS00866; CPSASE_1; 1.
DR PROSITE; PS00867; CPSASE_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}.
FT DOMAIN 1..450
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 120..317
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT DOMAIN 1135..1211
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
FT REGION 771..796
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1213 AA; 131211 MW; 0689369FC9878F68 CRC64;
MFDKLLIANR GAIACRILRT LRELNVSGVA VYAEADAASL HIQQADEAFC LGDGPAAQTY
LVVEKILDVA KRSGAKAIHP GYGFLSENAA FAEACEAAGI AFVGPTPEQL RVFGLKHTAR
ALAKQHGVPM LEGTELLENL DAALAAGEQV GYPVMLKSTA GGGGIGMRVC RSAAELSEAF
EAVKRLGQNN FSDSGVFIEK YIQRARHLEV QVFGDGQGEV LAFGVRDCSV QRRNQKVLEE
TPAPNLPAGM ADELCAAAIK LAKAVSYRSA GTVEFVYDSE AERFYFLEVN TRLQVEHGVT
EQVWGVDLVR WMIELAAGDL PPLSELAKTL EPSGHAIQAR LYAEDPGRDF QPSPGLLTAV
ALPPADGKAL RIDTWVEAGC EIPPYFDPMI AKLITWAPTR EEASAALDKA LADSVLYGVE
CNRDYLRQIL SDAPFASGHP WTRCLENLVY QPSTFEVLSA GTQTSVQDFP GRLGYWAVGV
PPSGPMDSRA LRLGNRLLGN AEGAAGLEIT MSGPLLRFNT DAVVAVTGAE IPLSVDGVEQ
PMNTALLIKA GTTLALGTIA GSGARSYLTL RGGLQVPEYL GSKSTFTLGQ FGGHGGRALR
AGDVLHLLPL TDTGSGAQLP AELCPTLPAV RELRVIYGPH GAPEYFSERY IDRFLATDWE
VHFNSSRTGV RLIGPKPEWV RDSGGEAGLH PSNIHDNPYA IGAVDFTGDM PVILGPDGPS
LGGFVCLVTI IEADLWQLGQ LKAGDKVRFV PVDIAAARAL AQGNARECTT LSRSGFSRDT
DGTPIADKSA PTDSTELSSP IVLDLGEGDT RLVARLSGDT HLLLEIGAPE LDLVLRFRGH
ALMQALEAKQ LDGVIDLTPG IRSLQVHYQP ETLSLARLLA AVIGEWDAVC NATDLRVPSR
IVHLPLSWDD PACQLAIEKY MTTVRKDAPW CPSNLEFIRR INDLPNLDEV YKTVFDASYL
VMGLGDVYLG APVATPLDPR HRLVTTKYNP ARTWTAENSV GIGGAYMCVY GMEGPGGYQF
VGRTLQMWNR YREVTAFHGK PWLLRFFDQI RFYPVSAEEL LQIRRDFPLG RYPLRIEHSE
LALADYQQFL ADEAAGIDAF RRQQRAAFAA ERQRWIESGQ AHFEVEEVAA ELGEDAPLGA
GQHGIDSHIA GNLWQVQVAE GARVEAGDVL VILESMKMEI PLTAPVAGTV REVRVQPGSP
VRAGQRVVVL EQA
//
