ID U2EHU6_9FIRM Unreviewed; 424 AA.
AC U2EHU6;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=HDIG domain protein {ECO:0000313|EMBL:ERI94152.1};
GN ORFNames=HMPREF1982_01164 {ECO:0000313|EMBL:ERI94152.1};
OS Clostridiales bacterium oral taxon 876 str. F0540.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=1321778 {ECO:0000313|EMBL:ERI94152.1, ECO:0000313|Proteomes:UP000016490};
RN [1] {ECO:0000313|EMBL:ERI94152.1, ECO:0000313|Proteomes:UP000016490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0540 {ECO:0000313|EMBL:ERI94152.1,
RC ECO:0000313|Proteomes:UP000016490};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERI94152.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AWSZ01000020; ERI94152.1; -; Genomic_DNA.
DR AlphaFoldDB; U2EHU6; -.
DR STRING; 1321778.HMPREF1982_01164; -.
DR PATRIC; fig|1321778.3.peg.1151; -.
DR eggNOG; COG2206; Bacteria.
DR HOGENOM; CLU_000445_92_14_9; -.
DR OrthoDB; 9804747at2; -.
DR Proteomes; UP000016490; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR006675; HDIG_dom.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF13487; HD_5; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS51832; HD_GYP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016490};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 234..424
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
FT DOMAIN 256..378
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 424 AA; 48714 MW; 3B4CCF51FA63C5E2 CRC64;
MKDLPLKLKV FLGLLYIFTV SSLVVLYNNV TFTFHRISYI EIVFFGILLA VAESFRIAYK
EMAISTGLAV LIASIILFGP LATSVIIVLG FSLRVRKIEN TYQHVFNIPI YQTLYNYCVQ
ILPVIYAGLV YYKLGGTFDT NNLWSKIFLI FIFSIICLLI NTFLISILFS ILNNKNPLYF
FISNIKLSLL NSFVMTPFGV GLAYMFSHYS YGGVLLIIFP IVLVRYTFYL YLESKNQYIE
TVDTLMHAME ARDKYTEGHS RRVSEISTKI AKQLKYDDLK IERIRIASLL HDVGKIGIDD
GILNKPGKLT KEEYEIIKSH PEIGYNILKD IKNLEDILPI IRNHHERYDG KGYPDKKMPE
ELSLDVFIVQ LADTIDAMAT DRPYRKALTE EEIISEITTY SGTQFHPKVV EAYLSILEKQ
KKAV
//
