ID U2ELZ6_9GAMM Unreviewed; 588 AA.
AC U2ELZ6;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Cell volume regulation protein A {ECO:0000313|EMBL:ERJ18930.1};
DE EC=6.3.4.3 {ECO:0000313|EMBL:ERJ18930.1};
GN Name=cvrA {ECO:0000313|EMBL:ERJ18930.1};
GN ORFNames=SSPSH_002007 {ECO:0000313|EMBL:ERJ18930.1};
OS Salinisphaera shabanensis E1L3A.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Salinisphaerales;
OC Salinisphaeraceae; Salinisphaera.
OX NCBI_TaxID=1033802 {ECO:0000313|EMBL:ERJ18930.1};
RN [1] {ECO:0000313|EMBL:ERJ18930.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E1L3A {ECO:0000313|EMBL:ERJ18930.1};
RX PubMed=21705588; DOI=10.1128/JB.05459-11;
RA Antunes A., Alam I., Bajic V.B., Stingl U.;
RT "Genome sequence of Salinisphaera shabanensis, a gammaproteobacterium from
RT the harsh, variable environment of the brine-seawater interface of the
RT Shaban Deep in the Red Sea.";
RL J. Bacteriol. 193:4555-4556(2011).
RN [2] {ECO:0000313|EMBL:ERJ18930.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E1L3A {ECO:0000313|EMBL:ERJ18930.1};
RX PubMed=24324765;
RA Alam I., Antunes A., Kamau A.A., Ba Alawi W., Kalkatawi M., Stingl U.,
RA Bajic V.B.;
RT "INDIGO - INtegrated Data Warehouse of MIcrobial GenOmes with Examples from
RT the Red Sea Extremophiles.";
RL PLoS ONE 8:E82210-E82210(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERJ18930.1}.
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DR EMBL; AFNV02000013; ERJ18930.1; -; Genomic_DNA.
DR RefSeq; WP_006914363.1; NZ_AFNV02000013.1.
DR AlphaFoldDB; U2ELZ6; -.
DR STRING; 1033802.SSPSH_002007; -.
DR eggNOG; COG3263; Bacteria.
DR OrthoDB; 9810759at2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:UniProtKB-EC.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR32507:SF7; K(+)_H(+) ANTIPORTER NHAP2; 1.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligase {ECO:0000313|EMBL:ERJ18930.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022449}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 491..570
FT /note="Transporter-associated"
FT /evidence="ECO:0000259|SMART:SM01091"
SQ SEQUENCE 588 AA; 63782 MW; EF28D9890621C129 CRC64;
MTDTNVILFF VGLLLFLSVV ASSLSRFGPP LLLIFLIVGM LAGQDGPGQI DFDNVPLAFF
IANLALAIIL LDGGLRTHLQ TFRVALWPAL SLATFGVLIS ASLAGAFIAV WLDLDWRYGL
LLGSIVASTD AAAVFSQLRS SGVTLNQRVS ATLEIESGTN DPMAIFMVTF LLATIDASKG
FNASSIASEI VSQFGIGIAG GLLLGYGLSF LASRMRLVEG LYALLVASGG LMAFTAINQL
GGSGFLGIYL VGLIVGNRRN HASEHVFRVM DGLAWLAQAG MFLVLGLLVN PHQLWAHAGS
AILVAAFLMF VARPLAVWLS LLPFNFPSRE QGFIAWVGLR GAVPIVLSLF PLMAELEGAQ
FLFDITFAVV LVSLIVQGSS LAWTARQLKL QVPREPGPTA SFGFLGQRGH SYVLLAFRIQ
TASSLAATQG DALHRFEGLR CIAVTRAAHL LFPKEHFVYA VGDLLYLITP AHHSDELGKL
FRGDTKHAPQ ARRFFGSFTL RGDAPISELA GIYDLGLAER DWDLSIADYM RRRLKRRPVE
GDVVDIDSLR LTVRSLHAGI IETVGLQLRE PEEAEGDHKS HKRRNRRH
//
