ID U2EPE2_9FIRM Unreviewed; 315 AA.
AC U2EPE2;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Arginine utilization regulatory protein RocR family protein {ECO:0000313|EMBL:ERI94841.1};
GN ORFNames=HMPREF1982_00766 {ECO:0000313|EMBL:ERI94841.1};
OS Clostridiales bacterium oral taxon 876 str. F0540.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=1321778 {ECO:0000313|EMBL:ERI94841.1, ECO:0000313|Proteomes:UP000016490};
RN [1] {ECO:0000313|EMBL:ERI94841.1, ECO:0000313|Proteomes:UP000016490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0540 {ECO:0000313|EMBL:ERI94841.1,
RC ECO:0000313|Proteomes:UP000016490};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERI94841.1}.
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DR EMBL; AWSZ01000016; ERI94841.1; -; Genomic_DNA.
DR AlphaFoldDB; U2EPE2; -.
DR STRING; 1321778.HMPREF1982_00766; -.
DR PATRIC; fig|1321778.3.peg.759; -.
DR eggNOG; COG3829; Bacteria.
DR HOGENOM; CLU_000445_0_7_9; -.
DR OrthoDB; 9803970at2; -.
DR Proteomes; UP000016490; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR PANTHER; PTHR32071:SF74; TRANSCRIPTIONAL ACTIVATOR ROCR; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016490};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..242
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 315 AA; 35431 MW; 2B7FB7AE85707AE1 CRC64;
MGDLGKAKYC FGDIIGISEN IKSCINKAQK AANTLSPVLI FGETGTGKEL FVQSIHNASA
RCRNPFIAQN CAAIPSGLLE SVLFGTKKGS FTGSEDKKGL FELADTGTLY LDELNSMPFE
LQGKILRVLQ EKVISKVGDN SLKKVDVRVI VSLNECPEYL IEKGTLRKDL YYRLNVVRID
IPPLRNRKED ILCLVEFFIE KFNKSFNASI TGIEEEALAS LVFWNWDGNV RELEHIIERV
FNYKTQGDIA IYDLINSGFK KSKRTKSLYE KVDEFEKTCI LEALVAAKSN ISKAAELLEI
PRQTLQSKMK RLNIK
//
