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Database: UniProt
Entry: U2HFS5_9BURK
LinkDB: U2HFS5_9BURK
Original site: U2HFS5_9BURK 
ID   U2HFS5_9BURK            Unreviewed;       228 AA.
AC   U2HFS5;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   03-JUL-2019, entry version 31.
DE   RecName: Full=Urease {ECO:0000256|SAAS:SAAS00108089};
DE            EC=3.5.1.5 {ECO:0000256|SAAS:SAAS00108089};
GN   ORFNames=L810_6169 {ECO:0000313|EMBL:ERJ39294.1};
OS   Burkholderia sp. AU4i.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=1335308 {ECO:0000313|EMBL:ERJ39294.1, ECO:0000313|Proteomes:UP000016616};
RN   [1] {ECO:0000313|EMBL:ERJ39294.1, ECO:0000313|Proteomes:UP000016616}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AU4i {ECO:0000313|EMBL:ERJ39294.1,
RC   ECO:0000313|Proteomes:UP000016616};
RA   Devi U., Khatri I., Kumar N., Kumar L., Singh D., Sharma D.,
RA   Subramanian S., Saini A.K.;
RT   "Genome Assembly of Burkholderia vietnamiensis AU4i.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+);
CC         Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16199, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938;
CC         EC=3.5.1.5; Evidence={ECO:0000256|SAAS:SAAS01115730};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3)
CC       from urea (urease route): step 1/1.
CC       {ECO:0000256|SAAS:SAAS00108095}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ERJ39294.1}.
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DR   EMBL; ASSI01000046; ERJ39294.1; -; Genomic_DNA.
DR   RefSeq; WP_012431165.1; NZ_ASSI01000046.1.
DR   EnsemblBacteria; ERJ39294; ERJ39294; L810_6169.
DR   PATRIC; fig|1335308.3.peg.2242; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000016616; Unassembled WGS sequence.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-EC.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00407; Urease_beta; 1.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   Gene3D; 3.30.280.10; -; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   InterPro; IPR008223; Urease_gamma-beta_su.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   InterPro; IPR036463; Urease_gamma_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   PIRSF; PIRSF001225; Urease_gammabeta; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   SUPFAM; SSF54111; SSF54111; 1.
DR   TIGRFAMs; TIGR00192; urease_beta; 1.
DR   TIGRFAMs; TIGR00193; urease_gam; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000016616};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00108092}.
SQ   SEQUENCE   228 AA;  24875 MW;  71EACB862AA506CC CRC64;
     MRLFPREVDR LLLHQAAQLA RSRRSRGLLL TEPEARALIA DTVCEGARVG GTVADMVALA
     STLLTDDDVM PGVTERVEVV MVEAFFPDGQ KLVCVHDPIG PGSQGEPQAP PPRWRLERTP
     VVVNRHRPTL RLRVASSADR PIQVGSHYHF FEVNPALAFD RHAAYGYRLD IPAATTLRFE
     PGDTRDVDLV AIGGARAVYG LAGLVNGALD DPAVRQVAMS RLAAFLEE
//
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