ID U2HIH5_9BURK Unreviewed; 556 AA.
AC U2HIH5;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Choline dehydrogenase {ECO:0000313|EMBL:ERJ38013.1};
GN ORFNames=L810_7580 {ECO:0000313|EMBL:ERJ38013.1};
OS Burkholderia sp. AU4i.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=1335308 {ECO:0000313|EMBL:ERJ38013.1, ECO:0000313|Proteomes:UP000016616};
RN [1] {ECO:0000313|EMBL:ERJ38013.1, ECO:0000313|Proteomes:UP000016616}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AU4i {ECO:0000313|EMBL:ERJ38013.1,
RC ECO:0000313|Proteomes:UP000016616};
RA Devi U., Khatri I., Kumar N., Kumar L., Singh D., Sharma D.,
RA Subramanian S., Saini A.K.;
RT "Genome Assembly of Burkholderia vietnamiensis AU4i.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERJ38013.1}.
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DR EMBL; ASSI01000073; ERJ38013.1; -; Genomic_DNA.
DR RefSeq; WP_021159560.1; NZ_ASSI01000073.1.
DR AlphaFoldDB; U2HIH5; -.
DR PATRIC; fig|1335308.3.peg.3585; -.
DR Proteomes; UP000016616; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003968}.
FT DOMAIN 83..106
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT BINDING 85
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 512
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 556 AA; 60638 MW; 43F4748F3A37F59A CRC64;
MKTDTFDYVI VGAGSAGCTL AYRLGEDPNV RILVLEAGEQ DRSPYIKVPL TWGQILKNRL
FDWGYFTEPE PGMDGRRIEC ARGKVVGGSS SINGMAYARG AREDYEGWVD EFGLTDWSYD
AVLPYFKRSE SWECGESSLR GGRGPLTVIR LDYRDPLIGG FLDATRACGY PENDDYNGAS
VEGFGPMQAT IRNGLRCSAA VAYLRPALAR GNVTLVAGAL ARRIVLDTDR GTPRATAIEY
RRGDTDYRAD ARREVILCGG VINSPQLLML SGIGATDHLR AHGIGTRVEL PGVGANLHDH
IVFDLRWSRK EPGPLHRMMR ADRIAFDVMR TLAGGNGFSG KIPAAALGLV RSQPHLPLPD
IQLILAAGAM NAAPYFEPFR HAYSDSFAIK GIFLTPESRG RVSLKSADPA QHARIEQNFL
ATENDRIAAR EMFRRMREIG AQAGLRPFID EEVAPGAHVQ SDADVDAFIR RIAITLHHPV
GTCRMGADDD AAAVVDTQMR VRGVTCLRVV DGSAIPRIIR GPTNALIMMM AERAADFMTG
KAVPVPQAPV RATAPM
//
