ID U2IPS9_9STRE Unreviewed; 742 AA.
AC U2IPS9;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Anaerobic ribonucleoside-triphosphate reductase {ECO:0000313|EMBL:ERJ75916.1};
GN ORFNames=HMPREF1557_01244 {ECO:0000313|EMBL:ERJ75916.1};
OS Streptococcus sobrinus W1703.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1227275 {ECO:0000313|EMBL:ERJ75916.1, ECO:0000313|Proteomes:UP000016617};
RN [1] {ECO:0000313|EMBL:ERJ75916.1, ECO:0000313|Proteomes:UP000016617}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W1703 {ECO:0000313|EMBL:ERJ75916.1,
RC ECO:0000313|Proteomes:UP000016617};
RA Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA Pepin K.H., Bhonagiri V., Zhang X., Warren W., Mitreva M., Mardis E.R.,
RA Wilson R.K.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERJ75916.1}.
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DR EMBL; AWVA01000080; ERJ75916.1; -; Genomic_DNA.
DR AlphaFoldDB; U2IPS9; -.
DR PATRIC; fig|1227275.3.peg.1102; -.
DR HOGENOM; CLU_002707_2_0_9; -.
DR Proteomes; UP000016617; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd01675; RNR_III; 1.
DR Gene3D; 3.20.70.20; -; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR019777; Form_AcTrfase_GR_CS.
DR InterPro; IPR001150; Gly_radical.
DR InterPro; IPR012833; NrdD.
DR NCBIfam; TIGR02487; NrdD; 1.
DR PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR Pfam; PF13597; NRDD; 1.
DR SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
DR PROSITE; PS00850; GLY_RADICAL_1; 1.
DR PROSITE; PS51149; GLY_RADICAL_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00492};
KW Organic radical {ECO:0000256|ARBA:ARBA00022818, ECO:0000256|PROSITE-
KW ProRule:PRU00493}.
FT DOMAIN 22..116
FT /note="ATP-cone"
FT /evidence="ECO:0000259|PROSITE:PS51161"
FT DOMAIN 605..731
FT /note="Glycine radical"
FT /evidence="ECO:0000259|PROSITE:PS51149"
FT MOD_RES 704
FT /note="Glycine radical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00493"
SQ SEQUENCE 742 AA; 84183 MW; 304F328B32B3E758 CRC64;
MVSEVERMIT LEKEFIVTDP EITVIKRDGR RLPFDSDKIY QALIKASQNV SNMSPLMEAK
LKGICDRIVA EIANRFMADI KIYEIQSIVE HELLNANEYA IAQEYINYRT QRDFARSQAT
DINFTIDKLI NKDQTVVNEN ANKDSDVFNT QRDLTAGIVG KSIGLKMLPP HVANAHQKGD
IHFHDLDYSP YTPMTNCCLI DFKGMLANGF KIGNAEVESP KSIQTATAQI SQIIANVASS
QYGGCTADRI DEFLAPYAEL NYQKHLKDAK EWVAEDKQED YARSKTKKDI YDAMQSLEYE
INTLFTSNGQ TPFTSLGFGL GTSWFEREIQ RAILQIRIKG LGSEHRTAIF PKLIFTLKRG
LNLEPGAPNY DIKQLALECA TKRMYPDVLS YDKIIDLTGS FKAPMGCRSF LQGWKDENGQ
EINSGRMNLG VVTVNLPRIA LESQGNMDKF WDIFAERMQI AKDALVYRVG RVKEASPANA
PILYQYGAFG KRLSKTGNVD DLFKNRRATV SLGYIGLYEV ATVFYGGEWE GNPEAKEFTK
DIIRQMKKLV EAWSDEYDYH FSIYSTPSES LTDRFCRLDT EKFGKVKDVT DKEYYTNSFH
YDVRKNPTPF EKLDFEKDYP ELGASGGFIH YCEYPVLQQN PKALEAVWDY AYDRVGYLGT
NTPIDKCYEC GFEGDFTPTE RGFMCPNCGN TDPKTVDVVK RTCGYLGNPQ ARPMVNGRHK
EISARVKHMN GSTINNPGQH EA
//
