ID   U2JD03_9STRE            Unreviewed;       449 AA.
AC   U2JD03;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=Trk system potassium uptake protein TrkA {ECO:0000256|ARBA:ARBA00017378};
GN   ORFNames=HMPREF1557_00488 {ECO:0000313|EMBL:ERJ77927.1};
OS   Streptococcus sobrinus W1703.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1227275 {ECO:0000313|EMBL:ERJ77927.1, ECO:0000313|Proteomes:UP000016617};
RN   [1] {ECO:0000313|EMBL:ERJ77927.1, ECO:0000313|Proteomes:UP000016617}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W1703 {ECO:0000313|EMBL:ERJ77927.1,
RC   ECO:0000313|Proteomes:UP000016617};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA   Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA   Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA   Pepin K.H., Bhonagiri V., Zhang X., Warren W., Mitreva M., Mardis E.R.,
RA   Wilson R.K.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERJ77927.1}.
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DR   EMBL; AWVA01000027; ERJ77927.1; -; Genomic_DNA.
DR   RefSeq; WP_019777040.1; NZ_KI259699.1.
DR   AlphaFoldDB; U2JD03; -.
DR   PATRIC; fig|1227275.3.peg.429; -.
DR   HOGENOM; CLU_046525_0_1_9; -.
DR   OrthoDB; 9775180at2; -.
DR   Proteomes; UP000016617; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR   InterPro; IPR006036; K_uptake_TrkA.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR003148; RCK_N.
DR   PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR   PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR   Pfam; PF02080; TrkA_C; 2.
DR   Pfam; PF02254; TrkA_N; 2.
DR   PRINTS; PR00335; KUPTAKETRKA.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR   SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR   PROSITE; PS51202; RCK_C; 2.
DR   PROSITE; PS51201; RCK_N; 2.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027}.
FT   DOMAIN          2..128
FT                   /note="RCK N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51201"
FT   DOMAIN          140..222
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
FT   DOMAIN          227..348
FT                   /note="RCK N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51201"
FT   DOMAIN          369..449
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
SQ   SEQUENCE   449 AA;  50140 MW;  F0D8B185244F21C5 CRC64;
     MKVIVVGGGK VGTALCRSLV EEKHDVTLIE EKEEVLGRVS RRLDIMGIVG NGANYKILEQ
     ADVQHCDIFV AISDQDEVNM ISAVLAKKMG AKETIVRVRN PEYSNAYFKD NNFLGFSMVV
     NPELLAARYI ANSVDFPGAL SVEHFVNGRI MLMEFKISEN NRLCDLSLEQ FRRKFGNILV
     CAIKRAGQVI IPDGDDILLK GDKIYVTGDR IEMILFHNFV KNKVIKNMMI IGAGRITYYL
     LNLLRNTKIK LKVIEITEKR SQYFSQEFPE IPIVLGDGTA KNILVEEGVE NYDAVATLTG
     VDEENIISSM FLDTLGIEKN ITKVNRTSLL EIIDTDDFSS IITPKSIAVD SMMHFIRGRV
     NAQESSTLDA VHHIANGKIE TLQFEIREKN KIAGKQLADV QLKKGVLVAA IIRKGKPLFP
     TGQDTYEVGD KIVVVTLLTN IADIYDLLK
//