ID   U2KMN0_9STRE            Unreviewed;       165 AA.
AC   U2KMN0;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Mutator MutT protein {ECO:0000313|EMBL:ERJ78459.1};
GN   ORFNames=HMPREF1557_00262 {ECO:0000313|EMBL:ERJ78459.1};
OS   Streptococcus sobrinus W1703.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1227275 {ECO:0000313|EMBL:ERJ78459.1, ECO:0000313|Proteomes:UP000016617};
RN   [1] {ECO:0000313|EMBL:ERJ78459.1, ECO:0000313|Proteomes:UP000016617}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W1703 {ECO:0000313|EMBL:ERJ78459.1,
RC   ECO:0000313|Proteomes:UP000016617};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA   Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA   Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA   Pepin K.H., Bhonagiri V., Zhang X., Warren W., Mitreva M., Mardis E.R.,
RA   Wilson R.K.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERJ78459.1}.
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DR   EMBL; AWVA01000014; ERJ78459.1; -; Genomic_DNA.
DR   AlphaFoldDB; U2KMN0; -.
DR   PATRIC; fig|1227275.3.peg.231; -.
DR   HOGENOM; CLU_037162_11_2_9; -.
DR   Proteomes; UP000016617; Unassembled WGS sequence.
DR   GO; GO:0008413; F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd03427; MTH1; 1.
DR   Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR   InterPro; IPR003562; Mutator_MutX_prot.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR020084; NUDIX_hydrolase_CS.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   PANTHER; PTHR43758; 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE; 1.
DR   PANTHER; PTHR43758:SF2; OXIDIZED PURINE NUCLEOSIDE TRIPHOSPHATE HYDROLASE; 1.
DR   Pfam; PF00293; NUDIX; 1.
DR   PRINTS; PR01402; MUTATORMUTX.
DR   SUPFAM; SSF55811; Nudix; 1.
DR   PROSITE; PS51462; NUDIX; 1.
DR   PROSITE; PS00893; NUDIX_BOX; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          6..138
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000259|PROSITE:PS51462"
SQ   SEQUENCE   165 AA;  19195 MW;  56BB9A39384F14E4 CRC64;
     MKEGSMTKLA TICYIDNGKE LLLMLRNKKP NDVHEGKWIS VGGKLEAGES PDECAKREIF
     EETHFTVKDM DFKGIITFPE FTPGHDWYTY VFKVTDFEGE LISDEESREG TLEWVPYDQV
     LSKPTWEGDY EIFKWILEDR PFFSAKFAYD SAGQLVEKSV TFYDK
//