ID U2L6G1_9BACT Unreviewed; 676 AA.
AC U2L6G1;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=HMPREF1218_1609 {ECO:0000313|EMBL:ERK00063.1};
OS Hoylesella pleuritidis F0068.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hoylesella.
OX NCBI_TaxID=1081904 {ECO:0000313|EMBL:ERK00063.1, ECO:0000313|Proteomes:UP000016600};
RN [1] {ECO:0000313|EMBL:ERK00063.1, ECO:0000313|Proteomes:UP000016600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0068 {ECO:0000313|EMBL:ERK00063.1,
RC ECO:0000313|Proteomes:UP000016600};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK00063.1}.
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DR EMBL; AWET01000040; ERK00063.1; -; Genomic_DNA.
DR RefSeq; WP_021584413.1; NZ_AWET01000040.1.
DR AlphaFoldDB; U2L6G1; -.
DR PATRIC; fig|1081904.3.peg.1833; -.
DR Proteomes; UP000016600; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ERK00063.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016600}.
FT DOMAIN 22..139
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 143..484
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT DOMAIN 551..671
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|Pfam:PF00754"
FT ACT_SITE 315
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 676 AA; 76872 MW; 2295A4261794ABE8 CRC64;
MRKKIFVCLW FWGIMLAVQG RNIIPQPNCL LWADGEFVFD DQTGLYTNLK GRDRKFIRSY
VAATLPVGRL KAKAVEMQNV VQLVLADSSA DMGTEGYRLM VTPQLITVRA SSATGLFYGL
QTLRQLCDGK RIRSVSVTDS PRFPYRGVML DCSRHFWSKD FILKQIDALA YFKLNRLHLH
LTDAGGWRME IKKYPKLISE SAYRTQSDWQ KWWNENDRRY CHKGDSSAYG GFYTQKELRE
IVRYAAQRRI TVIPEIEMPG HSNEVNHAYP ALSCTGEPLS DLCVGNEETF RFLENVLTEV
MRIFPSEYIH IGGDEAAREA WATCPRCRQR MRDEHLVTTA ELQSYLTARI ERFLNAHGRK
LLGWDEILEG KIAPRAAVMS WRGEQGGIDA SDAGHHVIMS PGGYCYLDKA QDAPGTQPKS
FGGYLPLEKV YGYEPVPEKF KGTNIEHFVD GVQGNLWTEY VDTEAHVEYM LYPRLLAIAE
RGWTWQPAPY DDFRRRALAA VAWMQHNGYH PFDLSKEIGR RPESRQAIVH LARGKTVFYK
APYAEKYKAA GDSALTDGQR GNWDFGDGVW QGFIGAGGLD AVIDMGTPTS VHCISVEFLQ
SVGPDIFAPA DVAISVSDDG KNFTSIYHKH TDRDTRREFF VADHRWTGDI TARYIRCQAQ
ADKQGGWIFA DEIVVK
//
