ID U2ME23_9FIRM Unreviewed; 977 AA.
AC U2ME23;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Putative calcium-translocating P-type ATPase, PMCA-type {ECO:0000313|EMBL:ERJ97528.1};
GN ORFNames=RUMCAL_00082 {ECO:0000313|EMBL:ERJ97528.1};
OS Ruminococcus callidus ATCC 27760.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=411473 {ECO:0000313|EMBL:ERJ97528.1, ECO:0000313|Proteomes:UP000016662};
RN [1] {ECO:0000313|EMBL:ERJ97528.1, ECO:0000313|Proteomes:UP000016662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27760 {ECO:0000313|EMBL:ERJ97528.1,
RC ECO:0000313|Proteomes:UP000016662};
RA Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERJ97528.1}.
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DR EMBL; AWVF01000014; ERJ97528.1; -; Genomic_DNA.
DR AlphaFoldDB; U2ME23; -.
DR STRING; 411473.RUMCAL_00082; -.
DR PATRIC; fig|411473.3.peg.70; -.
DR eggNOG; COG0474; Bacteria.
DR HOGENOM; CLU_002360_4_1_9; -.
DR Proteomes; UP000016662; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 3.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF156; CALCIUM-TRANSPORTING ATPASE; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 142..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 778..802
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 852..871
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 914..937
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 949..971
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 85..162
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
FT REGION 479..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 977 AA; 105678 MW; 091E4B38A86487A7 CRC64;
MHFQTSFLNW KNTLRIIIIQ TFPERISKRA PSFYRFQTDI LYYTWIRHNC QGVSCDFHKK
LSYVVMLFSF SAYSSHKQKH HLGRVWTALN KALFSVSLAK ERRHNMNGLT TKTARERLKQ
DGENELAAAA KRRPLRMFLG QFRDVMVLIL LAATGISAFL GEITDAVTII LIVLLNAILG
FLQEYRTEQT LESLRNLTAP TATACRDGKW QTIPARELVC GDLVRLEAGD NVPADSALIQ
AAGLAVNESI LTGESEAVSK QAGDPADTRN DLHKHNIVYA GTAILRGSAE AVVIATGTRT
QMGQISTMLQ EVRQEMTPLQ KRLAGLGKVV ALLCLGVCGA VFLAGVLRGE PVFDMLMTGI
TIAIAAIPEG LPATVTIALA LAVSRMMKHG ALVNRLHSVE TLGCASVICS DKTGTITENR
MTVTAIVAGG ERFSVTGTGL QKAGAIQLDG SNINPLSKPA LRELLTCGSL CSTAEIHSLQ
EKQSRNRGSR TEKGTWSATG DPTETALLIA AEKGGISRKA LLRTHPVQHM EPFNSETRRM
AVTVTDGAGT CTYWKGAADV ILPLCGFQMQ DGKSVPLSEG ARAAVRKQVA AMSDEALRVL
AFAKQEGSAC IFLGLAGMLD PPRESARTAI RTCAKANIRT VMITGDHKNT AAAIARQAGL
LRGKKAMTGA ELDTLTDAQL DRCIDQYSVF ARVNPAHKLR LVRAYKRRGE IVAMTGDGVN
DAPAIKEADV GVAMGKSGTD VARQAADVVL TDDNLATLVD AVEQGRCVYA NIRKFVRYLL
SCNIGEVLTM FLGILMGMPV VLLPTQLLLV NLVTDGLPAI ALGLEPPEPE AMQKPPRRPD
ESFFSDGLMG RIFFRGMLIG ICTLGAFSAV VRTGGTLEAA RTAALCTLIL SQLVHVFECK
SERRTLFSMP YGNNLWLVGA VLVSVAVLAA AVAVPMLRVI FSTVMLTRPQ WYIALGFSLT
VPLCSSIAGL FRRKKRD
//
