ID U2MHD7_9BACT Unreviewed; 594 AA.
AC U2MHD7;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Metallopeptidase family M24 {ECO:0000313|EMBL:ERK01060.1};
DE EC=3.4.-.- {ECO:0000313|EMBL:ERK01060.1};
GN ORFNames=HMPREF1218_0951 {ECO:0000313|EMBL:ERK01060.1};
OS Hoylesella pleuritidis F0068.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hoylesella.
OX NCBI_TaxID=1081904 {ECO:0000313|EMBL:ERK01060.1, ECO:0000313|Proteomes:UP000016600};
RN [1] {ECO:0000313|EMBL:ERK01060.1, ECO:0000313|Proteomes:UP000016600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0068 {ECO:0000313|EMBL:ERK01060.1,
RC ECO:0000313|Proteomes:UP000016600};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766, ECO:0000256|RuleBase:RU000590}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK01060.1}.
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DR EMBL; AWET01000032; ERK01060.1; -; Genomic_DNA.
DR RefSeq; WP_021584062.1; NZ_AWET01000032.1.
DR AlphaFoldDB; U2MHD7; -.
DR PATRIC; fig|1081904.3.peg.1404; -.
DR Proteomes; UP000016600; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ERK01060.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000590};
KW Reference proteome {ECO:0000313|Proteomes:UP000016600}.
FT DOMAIN 7..133
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 314..523
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 534..594
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 594 AA; 66419 MW; CBD8FD2EBEC4D041 CRC64;
MKTIQDRLSE LREVMHREHL AAFIFPSTDP HSGEYVPDHW MGRRWISGFN GSAGTVVVTM
HSAALWTDSR YFIAAADQLQ GSDFTLMKER IDGTPTIAEW IGRELQTSDL TEVGVDGWVC
SHSFVEQLRR ELREQGGITV RTNFDLLECI WKDRPAIPKN KVVVHPMEFA GERTASKIER
VRKALRAQHA DGTLVSALDD IAWILNLRGS DVHCNPVFVA YLLISSTQVT LYIDPDKLTP
EVVSYLKDEG VGIDDYADVR KGVADYDEYN ILLDPDRLND TLFHAPRVKQ IVAAASPVPS
LKAVKNEAEI AGFHRAMLRD GIAMVKFLHW LKPAVEAGGQ TEMSLDEMLT GLRAEQPLFK
GISFDTIVGY EQHGAIVHYE ATPETDVAVE PRGLVLIDSG AQYEDGTTDI TRTIALGPIT
DEQRRVYTLV LKGYIRLQRC KFPAGASGTQ LDILAREAMW REGLNYLHGT GHGVGSYLNV
HEGPHQIRME WRPAPIVAGM TVTDEPGIYL AGKFGVRIEN TLLAVPYKST DFGEFLQFEA
LTLCPIDKTP IIREMLSAEE VAWLNAYHRT VYERLAPHLD ASEKAWLKVA TEAI
//
