ID U2MLU8_9BACT Unreviewed; 942 AA.
AC U2MLU8;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA_2 {ECO:0000313|EMBL:ERK00219.1};
GN ORFNames=HMPREF1218_1341 {ECO:0000313|EMBL:ERK00219.1};
OS Hoylesella pleuritidis F0068.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hoylesella.
OX NCBI_TaxID=1081904 {ECO:0000313|EMBL:ERK00219.1, ECO:0000313|Proteomes:UP000016600};
RN [1] {ECO:0000313|EMBL:ERK00219.1, ECO:0000313|Proteomes:UP000016600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0068 {ECO:0000313|EMBL:ERK00219.1,
RC ECO:0000313|Proteomes:UP000016600};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK00219.1}.
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DR EMBL; AWET01000038; ERK00219.1; -; Genomic_DNA.
DR RefSeq; WP_021584298.1; NZ_AWET01000038.1.
DR AlphaFoldDB; U2MLU8; -.
DR PATRIC; fig|1081904.3.peg.1733; -.
DR Proteomes; UP000016600; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd03271; ABC_UvrA_II; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Hydrolase {ECO:0000313|EMBL:ERK00219.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016600};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 600..931
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 942 AA; 106162 MW; 5E7040E1CC2424E0 CRC64;
MEREDEKINV WGARVHNLKN IDVEIPRNSL TVITGLSGSG KSSLAFDTIF AEGQRRYIET
FSAYARNFLG GMERPDVDKI TGLSPVISIE QKTTNKNPRS TVGTTTEIYD YLRLLYARAG
TAYSYASGEK MVKYTEEKII TMILRDYADK RIFVLAPLVR QRKGHYRELF ESMRRKGYLY
VRIDGELKEI VRGMKVDRYK NHNIEVVIDK LQVQEKDDER LRRTIQVAMR QGDGVLMIMD
KDSGEIHNFS KRLMDPVTGI SYGEPAPNIF SFNSPEGACS KCKGLGYVNE IDLGKVIPDK
SASIHDGAII PLGKYKNQMI FWQIDAILQK YNCNVKTPVE KIPADALDEI LYGSLENVRI
SKELVHTSTD YFIAFDGVIK YLRNVMENDE TAAGQKWADQ FLATCKCPEC KGQRLKRESL
SYRIWDRNIS EVANMDIIEL REWLDNVEDH LDTTQRKIAT EIVKEIKTRV GFLLEVGLDY
LSLNRQSSSL SGGESQRIRL ATQIGSQLVN VLYILDEPSI GLHQRDNERL IHSLKELRDL
GNTVIVVEHD KDMMLNADYI IDIGPKAGRR GGEVIFQGSP QAMLNIRTIT ADYLTGKRKI
EAPKIYRAGN GKSIWIRGAR GNNLKNIDVE FPLGKLIVVT GVSGSGKSTL INETLQPILS
QHFYRSLKRP MPYTSIEGVD YIDKMVNVDQ SPIGRTPRSN PATYTGVFSD IRSLFVNLPE
AKIRGYKPGR FSFNVKGGRC EACGGNGYKV IEMNFLPDVM VPCEVCHGKR YNRETLEVRY
KGKSIADVLD MTINQAVEFF ENVPNILQKI KTIQDVGLGY IKLGQPSTTL SGGESQRVKL
ATELSKRDTG KTLYILDEPT TGLHFEDIRV LMDVLQKLVD KGNTVIIIEH NLDVIKLADY
IIDMGPEGGR GGGKVLSTGT PTKVARSKDG FTPRFLKQEF NS
//
