ID U2N715_9CLOT Unreviewed; 816 AA.
AC U2N715;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Pyridine nucleotide-disulfide oxidoreductase family protein {ECO:0000313|EMBL:ERK31312.1};
GN ORFNames=CINTURNW_1759 {ECO:0000313|EMBL:ERK31312.1};
OS Clostridium intestinale URNW.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1294142 {ECO:0000313|EMBL:ERK31312.1, ECO:0000313|Proteomes:UP000016721};
RN [1] {ECO:0000313|EMBL:ERK31312.1, ECO:0000313|Proteomes:UP000016721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=URNW {ECO:0000313|EMBL:ERK31312.1,
RC ECO:0000313|Proteomes:UP000016721};
RX PubMed=24136853;
RA Lal S., Ramachandran U., Zhang X., Sparling R., Levin D.B.;
RT "Draft Genome Sequence of the Hydrogen- and Ethanol-Producing Bacterium
RT Clostridium intestinale Strain URNW.";
RL Genome Announc. 1:e00871-13(2013).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the sulfur carrier protein TusA family.
CC {ECO:0000256|ARBA:ARBA00008984}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK31312.1}.
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DR EMBL; APJA01000012; ERK31312.1; -; Genomic_DNA.
DR RefSeq; WP_021801762.1; NZ_KI273145.1.
DR AlphaFoldDB; U2N715; -.
DR STRING; 1294142.CINTURNW_1759; -.
DR PATRIC; fig|1294142.3.peg.1791; -.
DR eggNOG; COG0446; Bacteria.
DR eggNOG; COG0607; Bacteria.
DR eggNOG; COG2210; Bacteria.
DR HOGENOM; CLU_003291_3_1_9; -.
DR OrthoDB; 9802028at2; -.
DR Proteomes; UP000016721; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd01524; RHOD_Pyr_redox; 1.
DR Gene3D; 3.40.1260.10; DsrEFH-like; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR Gene3D; 3.30.110.40; TusA-like domain; 1.
DR InterPro; IPR032836; DsrE2-like.
DR InterPro; IPR027396; DsrEFH-like.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR004099; Pyr_nucl-diS_OxRdtase_dimer.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR001455; TusA-like.
DR InterPro; IPR036868; TusA-like_sf.
DR PANTHER; PTHR43031; FAD-DEPENDENT OXIDOREDUCTASE; 1.
DR PANTHER; PTHR43031:SF1; PHAGE SHOCK PROTEIN E-RELATED PROTEIN; 1.
DR Pfam; PF13686; DrsE_2; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF02852; Pyr_redox_dim; 1.
DR Pfam; PF00581; Rhodanese; 1.
DR Pfam; PF01206; TusA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SMART; SM00450; RHOD; 1.
DR SUPFAM; SSF75169; DsrEFH-like; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR SUPFAM; SSF64307; SirA-like; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
DR PROSITE; PS01148; UPF0033; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000016721}.
FT DOMAIN 463..550
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
SQ SEQUENCE 816 AA; 89157 MW; BF0024DE1B0FC420 CRC64;
MKKVIIVGGV AGGASAATRL RRLDENLEII MFERGEYVSF ANCGLPYYIG GEIKEREKLL
VQTPKSINDR FNVDVRVNSD VVSIDTDRKV VKVNSLEKGE YEESYDYLIL SPGAKPIKPP
IKGIGSSKIY TLRNVPDTDK IKRVVDEKGI KSAVIIGGGF IGIEMAENLK ERGLDVTLIE
AAPHILAPFD SEMVTIAEKE LNDRDVSLIL NNGVDSFKDN NDLIEVHLKD GSFVESDIVI
LAIGVAPDTS FIRNTNIELG ARGHIIVDEY MRTSASDVYA VGDAILVKDY VSGEDVAIPL
AGPANRQGRI AADNIAGRKV AYKGTQGTSI LKIFDLVGAS TGNNERTLKR LGIDYKTAYI
HPMSHASYYP GAKQISIKLI FNKEGKVLGA QAFGYEGVDK FIDVIASVIK LNGTVEDLVE
LELAYAPPFL SAKSPQNMVG FVAENYLNGT TDIISVNELS VYNSENSTLL DIRETIEVES
GSIEGSINIP LNSLRNRLNE LPKDKEIIVY CAVGLRGHTA SRILTQNGFK VKNLSGGYKT
YIQSKYIAKK ISKQSNLNTD IKKEEVAVDI NSIELDACGL CCPGPLMQVK AKIDTLNTGD
VLKVKASDPG FYEDIKSWCK NTGNELMSLD KSCGIIYAEI KKKSKSNVEN VDILESSVKL
DNSQTMVVFS GDLDKAIASF IIANGAAAMG KKVTMFFTFW GLNILRKNEN IQVKKNIIEK
AFGFMMPRGS EKLSLSKMNM GGIGAKMIRG IMQKKNVQSL EELMKAAMDN GVNIVACTMS
MDIMGIKEEE LIDGVNFGGV GYYLGEASES NINLFI
//
