ID U2NSE1_9CLOT Unreviewed; 591 AA.
AC U2NSE1;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:ERK32073.1};
GN ORFNames=CINTURNW_0617 {ECO:0000313|EMBL:ERK32073.1};
OS Clostridium intestinale URNW.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1294142 {ECO:0000313|EMBL:ERK32073.1, ECO:0000313|Proteomes:UP000016721};
RN [1] {ECO:0000313|EMBL:ERK32073.1, ECO:0000313|Proteomes:UP000016721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=URNW {ECO:0000313|EMBL:ERK32073.1,
RC ECO:0000313|Proteomes:UP000016721};
RX PubMed=24136853;
RA Lal S., Ramachandran U., Zhang X., Sparling R., Levin D.B.;
RT "Draft Genome Sequence of the Hydrogen- and Ethanol-Producing Bacterium
RT Clostridium intestinale Strain URNW.";
RL Genome Announc. 1:e00871-13(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK32073.1}.
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DR EMBL; APJA01000007; ERK32073.1; -; Genomic_DNA.
DR RefSeq; WP_021800669.1; NZ_KI273145.1.
DR AlphaFoldDB; U2NSE1; -.
DR STRING; 1294142.CINTURNW_0617; -.
DR PATRIC; fig|1294142.3.peg.608; -.
DR eggNOG; COG0840; Bacteria.
DR eggNOG; COG4564; Bacteria.
DR HOGENOM; CLU_000445_107_19_9; -.
DR OrthoDB; 9810264at2; -.
DR Proteomes; UP000016721; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd11386; MCP_signal; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR033480; sCache_2.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF17200; sCache_2; 1.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016721};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 207..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 230..286
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 305..562
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 591 AA; 64734 MW; 45B2653733F573CE CRC64;
MKKIGTKIVL LTMLIAISTG IITGLTSVLQ INSIKQGFLN SKKEQMLNTY NQTIKEQVET
VITMLDGVNS KYKKGEITLA EAKSEGAALL RTIRYGKEGY FWADNIDGTN VAMLGQSVEG
TNRYESKDAN GTYFIKEIIK NGQNVDGGYT EYYFPKAGES EASAKRAYSK YYEPFGWVVG
TGNYIDTIDN TIAEESNIIS EMISKQVVTL ITIIGAIIIA AIAVGWIVGK RISKPILKVT
ELVNKTSKLD LAYDESFEVI KNYKDETGIM AEAVINLRKE IRGIIENLKE HAESLSTNSI
VSLEGAENTS NGIQAISATM EELAKGSVEQ AKNYQDIVDL FNNFTDKISH VVSGAEELKN
ISKNTKEANT KGRDSLDILV NKFEENKLAL EDIGQNIYAL WNQSTSIGSI VNKIGEIAEQ
TNLLALNAAI EAARAGEQGR GFAVVADEVR KLSEEVNNET KEIAAVIKEI QLEVNNSQKS
MDKGRELLVA VNSAVNDTTE VFNLIENSTD NSLEKINNLY TNINSVDKDK NGVMDSIQSV
SAITEESAAG LEEVSASMQE QNATTEIAVV LAEQLKAIST DLDEIINKFN I
//
