ID   U2P4U1_9BACT            Unreviewed;       550 AA.
AC   U2P4U1;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=HMPREF9135_2394 {ECO:0000313|EMBL:ERK39181.1};
OS   Segatella baroniae F0067.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Segatella.
OX   NCBI_TaxID=1115809 {ECO:0000313|EMBL:ERK39181.1, ECO:0000313|Proteomes:UP000016648};
RN   [1] {ECO:0000313|EMBL:ERK39181.1, ECO:0000313|Proteomes:UP000016648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0067 {ECO:0000313|EMBL:ERK39181.1,
RC   ECO:0000313|Proteomes:UP000016648};
RA   Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA   Methe B., Sutton G., Nelson K.E.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERK39181.1}.
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DR   EMBL; AWEY01000027; ERK39181.1; -; Genomic_DNA.
DR   RefSeq; WP_021589841.1; NZ_AWEY01000027.1.
DR   AlphaFoldDB; U2P4U1; -.
DR   ESTHER; 9bact-u2p4u1; Carb_B_Bacteria.
DR   PATRIC; fig|1115809.3.peg.1493; -.
DR   Proteomes; UP000016648; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016648};
KW   Signal {ECO:0000256|RuleBase:RU361235}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|RuleBase:RU361235"
FT   CHAIN           21..550
FT                   /note="Carboxylic ester hydrolase"
FT                   /evidence="ECO:0000256|RuleBase:RU361235"
FT                   /id="PRO_5005147452"
FT   DOMAIN          44..531
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   550 AA;  59602 MW;  28D28A59ADBC2499 CRC64;
     MKTKRIVAAL AALACLHACG HLTKEGRTAA ENTSEVVADS TTIVAKVKQG AIAGYQTMGV
     NVFKGVPYAK AERFMPPTAP DSWTGVRSCR AYGPTCPQAV RTGWQSDEAA FAFNWDDGHA
     GEDCLRLNIW TRGLADNKKR AVMVWLHGGG FAAGSGQELP AYDGTNLARK GDVVVVTVNH
     RLNVLGFLDL SAFGEKYGKS GNAGMLDLVE ALRWIKENVE SFGGDPDNVT IFGQSGGGGK
     VSTLLATPAA NGLFHKAIIE SGSQLKCMEQ QYTRRIGANV AKRLGLNASN IDRIAEMPYE
     KLLAAGEEAI KEEKAEALKA GWNGFIFGWG PVVDGDFLPQ HPFSPAAPAQ SKDIPLIIGT
     TLNEFCASAY VPALRNLSEE AVMQQVKQRY GNFADDYLKA FAEAYPDHKP NDLLDVDLTF
     RPMAMEQARL KEAQHGAPVY MYLFTWQSPA MNGIWRSIHC MEIPFVFDNT ALQGGMTGNG
     PQARALAQTM SQAWINFAKT GKPTAGGLPA WEAYTAANGA TLLFDNTCKM RYNHDAKLVK
     IARQCPQKPL
//