ID U2QNS5_9BACT Unreviewed; 1060 AA.
AC U2QNS5;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=HMPREF9135_1308 {ECO:0000313|EMBL:ERK40427.1};
OS Segatella baroniae F0067.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Segatella.
OX NCBI_TaxID=1115809 {ECO:0000313|EMBL:ERK40427.1, ECO:0000313|Proteomes:UP000016648};
RN [1] {ECO:0000313|EMBL:ERK40427.1, ECO:0000313|Proteomes:UP000016648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0067 {ECO:0000313|EMBL:ERK40427.1,
RC ECO:0000313|Proteomes:UP000016648};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERK40427.1}.
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DR EMBL; AWEY01000004; ERK40427.1; -; Genomic_DNA.
DR RefSeq; WP_021588464.1; NZ_AWEY01000004.1.
DR AlphaFoldDB; U2QNS5; -.
DR PATRIC; fig|1115809.3.peg.89; -.
DR Proteomes; UP000016648; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF64; ATP-DEPENDENT DNA HELICASE REP; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000016648}.
FT DOMAIN 1..469
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 493..743
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 9..16
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1060 AA; 123297 MW; 7F83EDBD666EF440 CRC64;
MASLTIYRAS AGAGKTFTLA VEYMTLLINN PYDFKRILAV TFTNKATEEM KLRILSQLYA
LAYLTGAKKN DYLLQIQDKT GLGEGVVRER AKMALHLLLH NFNYFRVETI DKFFQTVLRN
LARELELNAN LTVALNDIQI EEKAVDEMIE ELDGKSPVLH WIMEYISDSM QDDKSWNVID
KIKDFGRNIF KDEYKANVAG INERFHEKGF FNAFKKQLKS IEEEGDRHIK EQGDAFFELL
EQHGLQESDF KKNAVNYFTK LKTGRYVDEG EKNIVYNKSA REAAESADGW VRKADKTAGN
AAYELAESRL VEFISESETL RKRQLRQILS ARMIRQHIDQ LRLLKYIEEK VRDINNDHNR
FLLSNTQTLL HDLIGQSDSP FIFEKIGVML EHIMIDEFQD TSNIQWNNFK VLLKECMSHE
NAFNLIVGDV KQSIYRWRDG NWRLLNKLEQ QFNPQQVESE TLATNYRSDA NIIHFNNKFF
TFARQEEYDA LVKDTPAEAE ELLKAYSDVA QQIPMGKDEA RGLVEIKLLE SKSNSYVTET
LEHVGRKVQE LLDAGARESD IAILVRNNST IQDIGDYFME HMPHVRLVSD EAFHLDAALA
VNMLVMAMRV IADPTDQIAK AALLLNHRKN IKKTEERVTD ILIKGKSVDE QLPAAFIQHL
EELSVMPVMD MVEKLYHIFD LKDLDKQSAY VCAFFDELGN YLNENVADVV SFLKYWDEDL
HKKSIQSSEQ KGIRLITIHK SKGLEFDHVI MPFCDWLLEK RNTIWCKPTE APYDQLSLIP
VDFDKNKMLN SIFAQDYKIE HLQNMVDNLN LLYVGFTRAK RNLFVFGQKG CSDKNRSKLI
EDFIKGDSYS FGELDIPVEK ERDETKTDNI FEVKPQDVAI QIENYKTIVD FRQSNKSKDF
VNGEEDDEGT QRQYIKMGNV FHQIFASIRT TADIPTVLAT LEHDGVLFDN YLTYDKVKTM
LQRRFDNPTV KDWFSDRWDL HNECSILRYD SIAGKLLERR PDRVMTDGQE MIVVDFKFGT
PKEEHRRQVS EYMQLLREMG HANVKGYLWY VYTNKIDEVK
//
