ID   U2R9U6_LEIAQ            Unreviewed;       182 AA.
AC   U2R9U6;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE            EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
DE   Flags: Fragment;
GN   ORFNames=N136_01637 {ECO:0000313|EMBL:ERK72015.1};
OS   Leifsonia aquatica ATCC 14665.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Leifsonia.
OX   NCBI_TaxID=1358026 {ECO:0000313|EMBL:ERK72015.1, ECO:0000313|Proteomes:UP000016605};
RN   [1] {ECO:0000313|EMBL:ERK72015.1, ECO:0000313|Proteomes:UP000016605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14665 {ECO:0000313|EMBL:ERK72015.1,
RC   ECO:0000313|Proteomes:UP000016605};
RA   Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA   O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA   Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERK72015.1}.
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DR   EMBL; AWVQ01000203; ERK72015.1; -; Genomic_DNA.
DR   AlphaFoldDB; U2R9U6; -.
DR   HOGENOM; CLU_1485050_0_0_11; -.
DR   Proteomes; UP000016605; Unassembled WGS sequence.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016605}.
FT   DOMAIN          4..182
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
FT   NON_TER         182
FT                   /evidence="ECO:0000313|EMBL:ERK72015.1"
SQ   SEQUENCE   182 AA;  18910 MW;  EF5EA50101BC5153 CRC64;
     MLINLHTHLE GRVRPSTAAA LAPAAGLDAG IDWQRALELD APSDLTDYLA KVSSSYPFFG
     SRASLTRIAR EAVEDAHADG QSYLELRFGP ATHVRDGFGL TDVIAAVCEG VKQGIAITGM
     PAGVVVAALR LHDAETNEAV ARAAARFAGD GVVGFDLAGD EARFPDLHAF AGAFAIARAA
     GL
//