ID   U2RWA7_LEIAQ            Unreviewed;       299 AA.
AC   U2RWA7;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex family protein {ECO:0000313|EMBL:ERK73036.1};
DE   Flags: Fragment;
GN   ORFNames=N136_00594 {ECO:0000313|EMBL:ERK73036.1};
OS   Leifsonia aquatica ATCC 14665.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Leifsonia.
OX   NCBI_TaxID=1358026 {ECO:0000313|EMBL:ERK73036.1, ECO:0000313|Proteomes:UP000016605};
RN   [1] {ECO:0000313|EMBL:ERK73036.1, ECO:0000313|Proteomes:UP000016605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14665 {ECO:0000313|EMBL:ERK73036.1,
RC   ECO:0000313|Proteomes:UP000016605};
RA   Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA   O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA   Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000256|ARBA:ARBA00001938};
CC   -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00007317}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERK73036.1}.
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DR   EMBL; AWVQ01000056; ERK73036.1; -; Genomic_DNA.
DR   AlphaFoldDB; U2RWA7; -.
DR   PATRIC; fig|1358026.3.peg.514; -.
DR   HOGENOM; CLU_929102_0_0_11; -.
DR   Proteomes; UP000016605; Unassembled WGS sequence.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   Gene3D; 4.10.320.10; E3-binding domain; 1.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR036625; E3-bd_dom_sf.
DR   InterPro; IPR004167; PSBD.
DR   PANTHER; PTHR43178; DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; 1.
DR   PANTHER; PTHR43178:SF5; LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL; 1.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF02817; E3_binding; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
DR   SUPFAM; SSF47005; Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex; 1.
DR   PROSITE; PS51826; PSBD; 1.
PE   3: Inferred from homology;
KW   Pyruvate {ECO:0000313|EMBL:ERK73036.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016605};
KW   Transferase {ECO:0000313|EMBL:ERK73036.1}.
FT   DOMAIN          3..40
FT                   /note="Peripheral subunit-binding (PSBD)"
FT                   /evidence="ECO:0000259|PROSITE:PS51826"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ERK73036.1"
SQ   SEQUENCE   299 AA;  30800 MW;  A203EF806BACB45E CRC64;
     RPRATPPVRK LARERGIDLS AVTGTGARGL ITRQDLDAVA TGGPATAGGS HRLPVSATST
     AAVDTGRGDV RIPIRGVRKA TAEAMVRSAF SAPQATVFLT VDVSATSALV ERLRARTADG
     EARPGLLTVV AKALCLAIRR TPEVNARWDD DAQEIVQSGA VHLGIAAATP RGLLVPVVRD
     ADLLPLADLA GAIRTLAETA RSGRTAPADL SGSTITITNV GVFGVDAGTP IVTPGEAAIL
     ALGAVRRQPW EHDGGIALRD VLTLALSFDH RIVDGQQASV LLADLGRILS DPASVLAFV
//