ID   U2S1W6_9BACL            Unreviewed;       605 AA.
AC   U2S1W6;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=Putative epimerase/dehydratase WbiI {ECO:0000313|EMBL:ERK56807.1};
GN   ORFNames=HMPREF1983_01300 {ECO:0000313|EMBL:ERK56807.1};
OS   Gemella bergeri ATCC 700627.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Gemellaceae; Gemella.
OX   NCBI_TaxID=1321820 {ECO:0000313|EMBL:ERK56807.1, ECO:0000313|Proteomes:UP000016637};
RN   [1] {ECO:0000313|EMBL:ERK56807.1, ECO:0000313|Proteomes:UP000016637}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700627 {ECO:0000313|EMBL:ERK56807.1,
RC   ECO:0000313|Proteomes:UP000016637};
RA   Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA   O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA   Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERK56807.1}.
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DR   EMBL; AWVP01000080; ERK56807.1; -; Genomic_DNA.
DR   AlphaFoldDB; U2S1W6; -.
DR   PATRIC; fig|1321820.3.peg.1260; -.
DR   eggNOG; COG1086; Bacteria.
DR   HOGENOM; CLU_013560_5_2_9; -.
DR   Proteomes; UP000016637; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        32..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        62..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        99..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          275..562
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   605 AA;  67907 MW;  F8F67F5599CA4638 CRC64;
     MMIDLFIVAL GTLASIFLGR NSYPLEMLEN HGVSILEFVV LSLFIYGILF KIFGINKSLW
     SYLGVTEIVN ICTSILIADL FCGVLYQFML PDTFSNVRFV IFAPLLIVAG IMFIRMLYRA
     LRERENNIHG KNAYKNTLII GAGDAGYILL KELSKNNVFK ANVVGLIDDN RKNSIISGVN
     VLGTTYDLLK IIPKHEVEQV FLAIPSISTK DKNRILNILK EADVQVKVMG SGIALEEGES
     ISKHLKDVSI EDLLGRGEVK LSQGEVQSYI KGKSVLVTGA GGSIGSQIAR EVFKFKPKQL
     VLVDINENSL YMLERDLDFE KSHAKEYEQV NYISEIVSIR EKAALKEVFE KYKPDVVFHA
     AAHKHVPLME RRPQEAIKNN VFGTKNVMDV AIEYEVERFI MISTDKAVNP TNAMGASKRL
     TEIILQSKGA KYKTKFAAVR FGNVLGSNGS VIPIFKEQIK KGGPVTITHK NIIRYFMTIP
     EASQLVLQAG YYASSGEIFL LDMGEPVKII DLATNLIKLS GLEPYKDIDI EEIGLRPGEK
     MYEELSLDYE NSEKTDNKMI YKNTTLDIDI ATLDKQLEKL RTMLGNSTNE DIRKYLFEVI
     GKYNS
//