ID U2TIU1_9ACTN Unreviewed; 844 AA.
AC U2TIU1;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 03-MAY-2023, entry version 32.
DE SubName: Full=von Willebrand factor type A domain protein {ECO:0000313|EMBL:ERL06375.1};
GN ORFNames=HMPREF1316_1195 {ECO:0000313|EMBL:ERL06375.1};
OS Olsenella profusa F0195.
OC Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales; Atopobiaceae;
OC Olsenella.
OX NCBI_TaxID=1125712 {ECO:0000313|EMBL:ERL06375.1, ECO:0000313|Proteomes:UP000016638};
RN [1] {ECO:0000313|EMBL:ERL06375.1, ECO:0000313|Proteomes:UP000016638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0195 {ECO:0000313|EMBL:ERL06375.1,
RC ECO:0000313|Proteomes:UP000016638};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL06375.1}.
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DR EMBL; AWEZ01000067; ERL06375.1; -; Genomic_DNA.
DR AlphaFoldDB; U2TIU1; -.
DR STRING; 1125712.HMPREF1316_1195; -.
DR PATRIC; fig|1125712.3.peg.2197; -.
DR eggNOG; COG2304; Bacteria.
DR Proteomes; UP000016638; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 2.60.40.1140; Collagen-binding surface protein Cna, B-type domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR044060; Bacterial_rp_domain.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR Pfam; PF18998; Flg_new_2; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016638};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..844
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004634867"
FT TRANSMEM 818..838
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 241..469
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 123..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 844 AA; 89394 MW; 3BF8BB9DC604BD49 CRC64;
MMRKRFAKVW ITLTAIVLVA CFAMARGATV RTYAEDATSG TVTITFTAGE GGTLDPQDAL
TQTFAVGDAS DVAAVTARPS DGYAFVDWTC DGKEVSTDAT FTPPKKTAAY VANFKAVAAD
GTNADAKGTD TADGRGTVDD SDPTKGENLD HLTGPESSTG LPDNYSAPTA PGFGTGNGLR
NRLNAQLMRG NSPTGPTIGT DHPQSPGEVM LFKTATPVPG MVNTWDVTLR VEGKDSRKTS
DIVLVIDTSG SMRDNYRIEE AREAANSFVD TLLSNGGGSN THIAVVSYDS VVKTNQELTN
DAAALKRAIN GLRANGGTFT QAGIYRARQL LASSTADIKN IVLLSDGEPT YSYGILSPND
YLTAVGGHYE TSTAVPEGQF DHTSRVGNGG TLTQQYGWYR GREARYNNGN SAIAESGFAK
DDGSTMWTIA LEAGPRGTGI LQDIATPNHS YTASPSDLSQ IYQDIAGRIN DAVQDASVTD
PLGTGFSVPG GSIADITATQ GTASYDANEK RLHWDDLGTL TTPIDASHPD VKYAELHYRV
EVDDSILDAS PTDGMYATNG DARLSYIDTT GHRQDSPFPI PQVNPTLLVV EKRLYDKQGN
EVTSDDPSQT YAIHVTSSNG YDQTYDLRPG ERKVMTNLRL EDTYTVAETG YPSGTSAGDY
STTVTVYGQD TNTFAIRHDD PDTPVIVSNR EIPSLTVKKG VTGDLSDRTK KFDFDVTVTR
GGETILERTA SLADGEQEGI APDDGKVLLP GDHVTIKETN ADGYSASYTV DNGTATDGTG
VESSFSLAGD TTVSFTNSKQ DVPITGLVGS VGGSHAPLLI GVGAILAALS VAGTRFRFKF
RRGE
//
