ID U2UTD2_9ACTN Unreviewed; 400 AA.
AC U2UTD2;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:ERL06367.1};
GN ORFNames=HMPREF1316_1230 {ECO:0000313|EMBL:ERL06367.1};
OS Olsenella profusa F0195.
OC Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales; Atopobiaceae;
OC Olsenella.
OX NCBI_TaxID=1125712 {ECO:0000313|EMBL:ERL06367.1, ECO:0000313|Proteomes:UP000016638};
RN [1] {ECO:0000313|EMBL:ERL06367.1, ECO:0000313|Proteomes:UP000016638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0195 {ECO:0000313|EMBL:ERL06367.1,
RC ECO:0000313|Proteomes:UP000016638};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL06367.1}.
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DR EMBL; AWEZ01000067; ERL06367.1; -; Genomic_DNA.
DR RefSeq; WP_021727140.1; NZ_AWEZ01000067.1.
DR AlphaFoldDB; U2UTD2; -.
DR STRING; 1125712.HMPREF1316_1230; -.
DR PATRIC; fig|1125712.3.peg.2227; -.
DR eggNOG; COG0535; Bacteria.
DR OrthoDB; 9782387at2; -.
DR Proteomes; UP000016638; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21109; SPASM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000016638};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 17..153
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|Pfam:PF04055"
FT DOMAIN 241..299
FT /note="4Fe4S-binding SPASM"
FT /evidence="ECO:0000259|Pfam:PF13186"
SQ SEQUENCE 400 AA; 45836 MW; 3E8D28E161A88642 CRC64;
MAGRRVARGN EKLNGTVIVT YRCNARCTMC SRYKAPSRPE EEISLGTIAK LPRMYFTNIT
GGEPFIREDL KDVVRELYKR SDRIVISTNG FFTDRIVDLC KEFPDIGIRI SIEGLEQTNN
EIRGLQDGYQ RGYSTLKKLR DMGMTDVGFG MTVQDANAPD LVPLYRISNE MGMEFATASL
HNSFYFVEAR NIIHNRPMVA KNFEDLINEL LASNEPKKWF RAYFNHGLIN YIYGQPRLLP
CDMSYDTFFI DPYGDVMPCN GTKSKEVMGN LNEQTWDEVW NSVQADVVRG KVRHCDRNCW
MIGSVSPAMR KHILTPLRWV LVHKFLRAGR KKKYSMYENK VCRDYRDGKL TKEQLDRCST
CDHGAVADNG LSAASLEQLR HRTGEEIVGD DLKGQLGNTR
//
