ID U2V1T1_9ACTN Unreviewed; 572 AA.
AC U2V1T1;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Transketolase, thiamine pyrophosphate-binding domain protein {ECO:0000313|EMBL:ERL09297.1};
GN ORFNames=HMPREF1316_1852 {ECO:0000313|EMBL:ERL09297.1};
OS Olsenella profusa F0195.
OC Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales; Atopobiaceae;
OC Olsenella.
OX NCBI_TaxID=1125712 {ECO:0000313|EMBL:ERL09297.1, ECO:0000313|Proteomes:UP000016638};
RN [1] {ECO:0000313|EMBL:ERL09297.1, ECO:0000313|Proteomes:UP000016638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0195 {ECO:0000313|EMBL:ERL09297.1,
RC ECO:0000313|Proteomes:UP000016638};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL09297.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AWEZ01000030; ERL09297.1; -; Genomic_DNA.
DR AlphaFoldDB; U2V1T1; -.
DR STRING; 1125712.HMPREF1316_1852; -.
DR PATRIC; fig|1125712.3.peg.794; -.
DR eggNOG; COG2188; Bacteria.
DR eggNOG; COG3959; Bacteria.
DR Proteomes; UP000016638; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.1410.10; Chorismate lyase-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR028978; Chorismate_lyase_/UTRA_dom_sf.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR005474; Transketolase_N.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR011663; UTRA.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47514; TRANSKETOLASE N-TERMINAL SECTION-RELATED; 1.
DR PANTHER; PTHR47514:SF1; TRANSKETOLASE N-TERMINAL SECTION-RELATED; 1.
DR Pfam; PF00392; GntR; 1.
DR Pfam; PF00456; Transketolase_N; 1.
DR Pfam; PF07702; UTRA; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SMART; SM00866; UTRA; 1.
DR SUPFAM; SSF64288; Chorismate lyase-like; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016638}.
FT DOMAIN 39..107
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 572 AA; 61713 MW; EAB229E938E5D207 CRC64;
MIWIGQRDGW AMTGDRARFP TPETLDATRG QVDELGQSGP LHARLASLLR QKIVDREWPS
GMALPSEAEL MEQFCMSRGT VRRALSSLVQ DGYIVTRKGS GSFVAEGGLP RPATRRPLSF
AALFRERGLR FTTRVLSQSV MGAPRNVAIH LGVGEGSPVL FLRRIRSVGA RPLVCQESWE
SLRPCPGLER ADFTEESLFD AVERTSGRHI GSSVVHYSSQ RVGRAHAPLL ASEPESSTLV
LEQDICLTDG TPIEWSVTWM RPGTPVVGVS VEGPVREAAP SVGADGAEGG AGAAALRREL
DLRALEIRRG VLEIAHRYPH MPFHLGGALS MAEVVAVLLG HVMHTGADGT PWERRDRLVV
SKAHASVALY PALLRAGIIS QDDLDRGLFG PDAVLFKHPH RDPGRGIELS GGSLGMGLGY
ACGLALALRR RQLPARVFCI VGDGECDEGS VWESAAFAGH QRLSNLTVVV DANGMQLDGP
TAQVLDNGPL RRKFEAFGFA VAETDGHDVL ALARALAAPH EGPLAVVART VKGRGLSRAE
NNVAWHDIAL AQDDYERARV ELGQREEAIR HG
//
