ID U2ZSJ0_PSEA4 Unreviewed; 795 AA.
AC U2ZSJ0;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Putative two-component histidine kinase {ECO:0000313|EMBL:GAD64405.1};
GN ORFNames=PA6_037_00280 {ECO:0000313|EMBL:GAD64405.1};
OS Pseudomonas alcaligenes (strain ATCC 14909 / DSM 50342 / JCM 20561 / NBRC
OS 14159 / NCIMB 9945 / NCTC 10367 / 1577).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1215092 {ECO:0000313|EMBL:GAD64405.1, ECO:0000313|Proteomes:UP000016560};
RN [1] {ECO:0000313|EMBL:GAD64405.1, ECO:0000313|Proteomes:UP000016560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14909 / DSM 50342 / JCM 20561 / NBRC 14159 / NCIMB 9945 /
RC NCTC 10367 / 1577 {ECO:0000313|Proteomes:UP000016560};
RA Yoshida I., Hosoyama A., Tsuchikane K., Noguchi M., Hirakata S., Ando Y.,
RA Ohji S., Yamazoe A., Yamazaki S., Fujita N.;
RT "Whole genome shotgun sequence of Pseudomonas alcaligenes NBRC 14159.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD64405.1}.
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DR EMBL; BATI01000037; GAD64405.1; -; Genomic_DNA.
DR RefSeq; WP_021702487.1; NZ_BATI01000037.1.
DR AlphaFoldDB; U2ZSJ0; -.
DR STRING; 43263.A0T30_20055; -.
DR eggNOG; COG0834; Bacteria.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG3852; Bacteria.
DR eggNOG; COG4585; Bacteria.
DR OrthoDB; 9797605at2; -.
DR Proteomes; UP000016560; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR CDD; cd00130; PAS; 2.
DR CDD; cd01007; PBP2_BvgS_HisK_like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00062; PBPb; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:GAD64405.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016560};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 269..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 327..371
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 393..443
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 444..521
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 524..575
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 597..791
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 566..593
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 795 AA; 89078 MW; 067DB8195FB37272 CRC64;
MGVVRRIRVV CWLLLLCPLL GRASELDALQ RAWLAEHPQL RAGVVLQAPY AEYQRRQQQL
GGLNVELTET LASSLGVTLS WRSFETQAAL EQALRDGRID FAPGQVQTPA GLRLWRYSDP
YLRIPHLLVG ERLGEVSVEL ERLSEREPIA VRVPSMVADY LRSNYFNLHL QPQPSARQAL
QAVVEQRARY AVVDQAQLSR LSQESDYSRL AIIADVGLPQ LLRFGTRPDW PQLGAILDTG
LRQLPAEQLE QLQQRWLTAK KPGLGESPLF WRSLSILLGL LLAVCILLLS VLRRQRGRLE
KRLLEARQTL AQREVAEEAL RLAQFSLDHS TVGILWVNWD SRVRYANQAV AEMLGYTPQA
MVDRALQEFE PTLGMDRWLT LWKRVRQHEE GALSFESSCR RADGSTMPAD VTLGFLRFRE
AEYLVVYLTD VTERRRARAA LEESEARLKG IAGNVPGLVF RLERPRPGAL VDFAFISEGS
EQLVGYPPAT IMATDFGIRS LVHPEDRAAY HATQDAAIEA AGDWQWQGRI LTRDGRVRWA
DIKASARQLS AEHVVWDGVV WDISDNKAIE LELAESRAQL RELSAHLESV REEEKARIAR
EVHDELGQVL TVLKLETSMC ELAYAGLDPG LQVRLDSMKK LIANLFQLVR DVATALRPPI
LDAGIASAIE WQARRFEARS GIPCLVQVPE QLPQLSDAKA IGLFRVLQEA LTNVLRHAQA
HTVEIALEVQ GGELCLRVSD DGRGFDPQAQ RAQSFGLVGM RERVLMLGGR LALDSTPGEG
TTLVVRVALD EEVVA
//
