ID   U3A5Z2_9SPHN            Unreviewed;       550 AA.
AC   U3A5Z2;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Putative 3-ketosteroid delta(1)-dehydrogenase {ECO:0000313|EMBL:GAD50163.1};
GN   ORFNames=NT2_07_01630 {ECO:0000313|EMBL:GAD50163.1};
OS   Caenibius tardaugens NBRC 16725.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Erythrobacteraceae; Caenibius.
OX   NCBI_TaxID=1219035 {ECO:0000313|EMBL:GAD50163.1, ECO:0000313|Proteomes:UP000016568};
RN   [1] {ECO:0000313|EMBL:GAD50163.1, ECO:0000313|Proteomes:UP000016568}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 16725 {ECO:0000313|EMBL:GAD50163.1,
RC   ECO:0000313|Proteomes:UP000016568};
RA   Isaki S., Hosoyama A., Tsuchikane K., Katsumata H., Ando Y., Yamazaki S.,
RA   Fujita N.;
RT   "Whole genome shotgun sequence of Novosphingobium tardaugens NBRC 16725.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAD50163.1}.
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DR   EMBL; BASZ01000007; GAD50163.1; -; Genomic_DNA.
DR   RefSeq; WP_021690981.1; NZ_CP034179.1.
DR   AlphaFoldDB; U3A5Z2; -.
DR   KEGG; ntd:EGO55_05950; -.
DR   eggNOG; COG1053; Bacteria.
DR   OrthoDB; 3178130at2; -.
DR   Proteomes; UP000016568; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR   PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE   4: Predicted;
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016568}.
FT   DOMAIN          12..529
FT                   /note="FAD-dependent oxidoreductase 2 FAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF00890"
SQ   SEQUENCE   550 AA;  59408 MW;  B76B2BCD8D4682B7 CRC64;
     MAEDMEWDLE ADVVVLGSGG AAMTAAISAY DFGAKDVVIL EKSGMVGGTT AMSGGMLWIP
     NNPYQVEAGI ADSDEDIVAY LDALAPGQLE PDTLGAFMES GPEMIRYFMD KTPVRFHVYT
     DFPDYQPYIP GAKPDGGRSL DNEAFSFETL GKWATRVNPT KMAYPVRGSL MEAINGTLDE
     ATLAEREARD YRGLGQALAG SLFKAVLDRG IPVEFEKRAR KLVKDGERVI GVIAEDGNGR
     DFRVRARRGV VIATGGFEWN ETLVKIFLRG PLTGPVSVPE NEGDGLLMAI EAGAQLGNMQ
     HAFWQQSVLE FKPQHRSAKP NYLLGSDERA RPGAILVNKA GKRFVNEAAN YNAMGKALHA
     FDAGTHTYAN LPYWLIIDQR YKNKYHTFNS PPGGPVPSFM MQADTLEALA ELAGIDPQGL
     TATVARFNDL VRNGHDDDFN RGDNTYDNFY MWGDSDFDPP HRTLGVIDQG PFYAVKMESG
     ALGTSGGPRT NGDAQVLDWA GNPIPGLYAA GNAMAAVLGE AYGGAGGTLG PGMTFGYIAG
     RHLGTHIPNR
//