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Database: UniProt
Entry: U3ABC3_9RHOB
LinkDB: U3ABC3_9RHOB
Original site: U3ABC3_9RHOB 
ID   U3ABC3_9RHOB            Unreviewed;       247 AA.
AC   U3ABC3;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   RecName: Full=Heme exporter protein C {ECO:0000256|ARBA:ARBA00016463, ECO:0000256|RuleBase:RU364092};
DE   AltName: Full=Cytochrome c-type biogenesis protein {ECO:0000256|RuleBase:RU364092};
GN   Name=ccmC {ECO:0000256|RuleBase:RU364092};
GN   ORFNames=MBELCI_1016 {ECO:0000313|EMBL:GAD54964.1};
OS   Limimaricola cinnabarinus LL-001.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Limimaricola.
OX   NCBI_TaxID=1337093 {ECO:0000313|EMBL:GAD54964.1, ECO:0000313|Proteomes:UP000016566};
RN   [1] {ECO:0000313|EMBL:GAD54964.1, ECO:0000313|Proteomes:UP000016566}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LL-001 {ECO:0000313|EMBL:GAD54964.1,
RC   ECO:0000313|Proteomes:UP000016566};
RA   Nishi S., Tsubouchi T., Takaki Y., Koyanagi R., Satoh N., Maruyama T.,
RA   Hatada Y.;
RT   "Draft Genome Sequence of Loktanella cinnabarina LL-001T, Isolated from
RT   Deep-Sea Floor Sediment.";
RL   Genome Announc. 1:e00927-13(2013).
CC   -!- FUNCTION: Required for the export of heme to the periplasm for the
CC       biogenesis of c-type cytochromes. {ECO:0000256|ARBA:ARBA00002442,
CC       ECO:0000256|RuleBase:RU364092}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU364092}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CcmC/CycZ/HelC family.
CC       {ECO:0000256|ARBA:ARBA00005840, ECO:0000256|RuleBase:RU364092}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAD54964.1}.
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DR   EMBL; BATB01000008; GAD54964.1; -; Genomic_DNA.
DR   RefSeq; WP_021693072.1; NZ_BATB01000008.1.
DR   AlphaFoldDB; U3ABC3; -.
DR   STRING; 1337093.MBELCI_1016; -.
DR   eggNOG; COG0755; Bacteria.
DR   OrthoDB; 9778550at2; -.
DR   Proteomes; UP000016566; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR003557; Cyt_c_biogenesis_CcmC.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   NCBIfam; TIGR01191; ccmC; 1.
DR   PANTHER; PTHR30071:SF17; CYTOCHROME C ASSEMBLY PROTEIN-RELATED; 1.
DR   PANTHER; PTHR30071; HEME EXPORTER PROTEIN C; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   PRINTS; PR01386; CCMCBIOGNSIS.
PE   3: Inferred from homology;
KW   Cell inner membrane {ECO:0000256|RuleBase:RU364092};
KW   Cell membrane {ECO:0000256|RuleBase:RU364092};
KW   Cytochrome c-type biogenesis {ECO:0000256|RuleBase:RU364092};
KW   Lyase {ECO:0000313|EMBL:GAD54964.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364092};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU364092};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU364092}; Transport {ECO:0000256|RuleBase:RU364092}.
FT   TRANSMEM        20..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        93..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   TRANSMEM        199..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364092"
FT   DOMAIN          26..183
FT                   /note="Cytochrome c assembly protein"
FT                   /evidence="ECO:0000259|Pfam:PF01578"
SQ   SEQUENCE   247 AA;  27594 MW;  AC389EB50A42AE6F CRC64;
     MSIWSYANPR KFLETTAPWV PWLMWLSAAV LAVGLVWGFF FTPEAERFGS SVKIIYLHVP
     SALMAINAWL MMLVASLIWL VRRHHVSALA ARAAAPIGMV MTLIALVTGA IWGQPMWGTW
     WAWDPRLTSF LILFLFYLGY IALWAAIPDP DSAADLTSVL CLVGSVFAIL SRYAVNFWNQ
     GLHQGASLSL DSQENVADVF WLPLLVCMAG FVLLFVSLVL LRTGTEIRAR RIAAMRARAR
     RAEPVRA
//
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