ID U3BFB2_CALJA Unreviewed; 834 AA.
AC U3BFB2; F7I8P7;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Enhancer of filamentation 1 isoform 1 {ECO:0000313|EMBL:JAB04364.1};
GN Name=NEDD9 {ECO:0000313|EMBL:JAB04364.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB04364.1};
RN [1] {ECO:0000313|EMBL:JAB04364.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB04364.1}, Hippocampus
RC {ECO:0000313|EMBL:JAB14136.1}, and Skeletal muscle
RC {ECO:0000313|EMBL:JAB36274.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
CC -!- SUBCELLULAR LOCATION: Cell junction, focal adhesion
CC {ECO:0000256|ARBA:ARBA00004246}.
CC -!- SIMILARITY: Belongs to the CAS family. {ECO:0000256|ARBA:ARBA00007848}.
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DR EMBL; GAMT01007497; JAB04364.1; -; mRNA.
DR EMBL; GAMS01009000; JAB14136.1; -; mRNA.
DR EMBL; GAMQ01005577; JAB36274.1; -; mRNA.
DR AlphaFoldDB; U3BFB2; -.
DR Bgee; ENSCJAG00000005060; Expressed in ovary and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd11570; FAT-like_NEDD9_C; 1.
DR CDD; cd11550; Serine_rich_NEDD9; 1.
DR CDD; cd12002; SH3_NEDD9; 1.
DR Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 1.
DR Gene3D; 1.20.120.830; Serine-rich domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR021901; CAS_C.
DR InterPro; IPR037362; CAS_fam.
DR InterPro; IPR035746; NEDD9_SH3.
DR InterPro; IPR014928; Serine_rich_dom.
DR InterPro; IPR038319; Serine_rich_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR10654; CAS SCAFFOLDING PROTEIN; 1.
DR PANTHER; PTHR10654:SF20; ENHANCER OF FILAMENTATION 1; 1.
DR Pfam; PF12026; CAS_C; 1.
DR Pfam; PF08824; Serine_rich; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 2: Evidence at transcript level;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 3..65
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 237..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 834 AA; 92939 MW; 77A096BD1A370CA0 CRC64;
MKYKNLMARA LYDNVPECAE ELAFRKGDIL TVIEQNTGGL EGWWLCSLHG RQGIVPGNRV
KLLIGPVQEN ASSHEQPVSG LMQQTFGQQK LYQVPNPQAA PRDTIYQVPS SYQNQGIYQV
PTGHGTQEQE VYQVPPSVQR SLGGTSGPHG GKKVITPVRT GHGYVYEYPS RYQKDVYDIP
PSHTTQGVYD IPPSSVKGPM FSVPVGEIKP QGVYDIPPTK GVYAIPPSAC RDEAGFREKD
YDFPPPMRQA GRPDLRPEGV YDIPPTSTKP AGKDLHVKYN CDIPGAAEPV ARRHQSLSPN
HPPPQLGQSV GPQNDAYDVP RGIQFLEPPA ETSEKPNPQE RDGVYDVPLH NPPDAKGSRD
LVDGINRLSF SSTGSTRSNM STSSTSSKES SLSASPAQDK RLLLDPDTAI ERLQRLQQAL
EMGVSSLMAL VTTDWRCYGY MEKHINEIRT SVEKVELFLK EYLHFVKGAV ANASCLPELI
LHNKMKRELQ RVEDSHQILS QTSHDLNECS WSLNILAINK PQNKCDDLDR FVMVAKTVPD
DAKQLTTTIN TNAETLFKPG PGSLHLKNGP ESIMNSTEYP HGSPQVQLLH PGDHKAQAHS
KALPPGLGKE QAPDCSSSDG SERSWMDDYD YVHLQGKEEF ERQQKELLEK ENIIKQNKMQ
LEHHQLSQFQ LLEQEITKPV ENDISKWKPS QSLPTTNSGV SAQDRQLLCF YYDQCETHFI
SLLNAIDALF SCVSSAQPPR IFVAHSKFVI LSAHKLVFIG DTLTRQVTAQ DIRNKVMNSS
NQLCEQLKTI VMATKMAALH YPSTTALQEM VHQVTDLSRN AQLFKRSLLE MATF
//
