ID U3BPG0_CALJA Unreviewed; 351 AA.
AC U3BPG0; F7IRQ3;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Nuclear inhibitor of protein phosphatase 1 isoform alpha {ECO:0000313|EMBL:JAB07699.1};
DE SubName: Full=Protein phosphatase 1 regulatory subunit 8 {ECO:0000313|Ensembl:ENSCJAP00000017280.2};
GN Name=PPP1R8 {ECO:0000313|EMBL:JAB07699.1,
GN ECO:0000313|Ensembl:ENSCJAP00000017280.2};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB07699.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000017280.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB07699.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB07699.1}, and Hippocampus
RC {ECO:0000313|EMBL:JAB16071.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000017280.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; GAMT01004162; JAB07699.1; -; mRNA.
DR EMBL; GAMS01007065; JAB16071.1; -; mRNA.
DR RefSeq; XP_017829947.1; XM_017974458.1.
DR STRING; 9483.ENSCJAP00000017280; -.
DR Ensembl; ENSCJAT00000018277.4; ENSCJAP00000017280.2; ENSCJAG00000009406.5.
DR GeneID; 100393315; -.
DR KEGG; cjc:100393315; -.
DR CTD; 5511; -.
DR eggNOG; KOG1880; Eukaryota.
DR GeneTree; ENSGT00940000156115; -.
DR HOGENOM; CLU_069628_0_0_1; -.
DR OMA; NSTFHFG; -.
DR OrthoDB; 4248727at2759; -.
DR TreeFam; TF105539; -.
DR Proteomes; UP000008225; Chromosome 7.
DR Bgee; ENSCJAG00000009406; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0016607; C:nuclear speck; IEA:Ensembl.
DR GO; GO:0019888; F:protein phosphatase regulator activity; IEA:Ensembl.
DR GO; GO:0008283; P:cell population proliferation; IEA:Ensembl.
DR CDD; cd22674; FHA_PPP1R8; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.1290; -; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR23308:SF53; KANADAPTIN-RELATED; 1.
DR PANTHER; PTHR23308; NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1; 1.
DR Pfam; PF00498; FHA; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 49..101
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 316..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 351 AA; 38479 MW; 0A0E92B033E37641 CRC64;
MAAAANSGSS LPLFDCPTWA GKPPPGLHLD VVKGDKLIEK LIIDEKKYYL FGRNPDLCDF
TIDHQSCSRV HAALVYHKHL KRVFLIDLNS THGTFLGHIR LEPHKPQQIP IDSTVSFGAS
TRAYTLREKP QTLPSAVKGD EKMGGEDDEL KGLLGLPEEE TELDNLTEFN TAHNKRISTL
TIEEGNLDIQ RPKRKRKNSR VTFSEDDEII NPEDVDPSVG RFRNMVQTAV VPVKKKRVEG
PGSLGLEESG SRRMQNFAFS GGLYGGLPPT HSEAGSQPHG IHGTALIGGL PMPYPNLAPD
VDLTPVVPSA VNMNPAPNPA VYNPEAVNEP KKKKYAKEAW PGKKPTPSLL I
//
