ID   U3C4I6_9VIBR            Unreviewed;       295 AA.
AC   U3C4I6;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN   ORFNames=VAZ01S_041_00140 {ECO:0000313|EMBL:GAD76314.1};
OS   Vibrio azureus NBRC 104587.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=1219077 {ECO:0000313|EMBL:GAD76314.1, ECO:0000313|Proteomes:UP000016567};
RN   [1] {ECO:0000313|EMBL:GAD76314.1, ECO:0000313|Proteomes:UP000016567}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 104587 {ECO:0000313|EMBL:GAD76314.1,
RC   ECO:0000313|Proteomes:UP000016567};
RA   Isaki S., Hosoyama A., Numata M., Hashimoto M., Hosoyama Y., Tsuchikane K.,
RA   Noguchi M., Hirakata S., Ichikawa N., Ohji S., Yamazoe A., Fujita N.;
RT   "Whole genome shotgun sequence of Vibrio azureus NBRC 104587.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAD76314.1}.
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DR   EMBL; BATL01000041; GAD76314.1; -; Genomic_DNA.
DR   AlphaFoldDB; U3C4I6; -.
DR   STRING; 1219077.VAZ01S_041_00140; -.
DR   eggNOG; COG0491; Bacteria.
DR   Proteomes; UP000016567; Unassembled WGS sequence.
DR   GO; GO:0008800; F:beta-lactamase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0017001; P:antibiotic catabolic process; IEA:InterPro.
DR   CDD; cd16280; metallo-hydrolase-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR001018; Beta-lactamase_class-B_CS.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   PANTHER; PTHR23131; ENDORIBONUCLEASE LACTB2; 1.
DR   PANTHER; PTHR23131:SF0; ENDORIBONUCLEASE LACTB2; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR   PROSITE; PS00743; BETA_LACTAMASE_B_1; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016567}.
FT   DOMAIN          68..268
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   295 AA;  33086 MW;  4362F4B7B2490B59 CRC64;
     MFTVELARAK TKQSIFVGYF VKKTILAVLF SASVFASSSK DVPTMNDKNG YVEPFQMFDN
     VYYVGDKWVS SYAIDTDDGL VIIDTLDFPY SKWISINLEK LGLEDKPITH ILVTHGHSDH
     VGGAQLLQKM YGSKVVMTKS AHELSIQQSN KSKGEKQFLS PTLDIEIKSD TSMVIGGKEF
     KFYLTPGHTE GDFSLDFTVK DKGAEHRAFV VGGHSVSGND PKMINQFLNS IEKVRKIALQ
     SPLVSVNLSN HPHKNYLFEN REKLVVNGNP FISETNFFMF LKQQESLAKN KIKGL
//