ID U3CU98_9VIBR Unreviewed; 560 AA.
AC U3CU98;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Long-chain-fatty-acid--CoA ligase {ECO:0000256|ARBA:ARBA00039545};
DE EC=6.2.1.3 {ECO:0000256|ARBA:ARBA00026121};
DE AltName: Full=Long-chain acyl-CoA synthetase {ECO:0000256|ARBA:ARBA00042773};
GN Name=fadD {ECO:0000313|EMBL:GAD81308.1};
GN ORFNames=VEZ01S_55_00250 {ECO:0000313|EMBL:GAD81308.1};
OS Vibrio ezurae NBRC 102218.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=1219080 {ECO:0000313|EMBL:GAD81308.1, ECO:0000313|Proteomes:UP000016562};
RN [1] {ECO:0000313|EMBL:GAD81308.1, ECO:0000313|Proteomes:UP000016562}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 102218 {ECO:0000313|EMBL:GAD81308.1,
RC ECO:0000313|Proteomes:UP000016562};
RA Yoshida I., Hosoyama A., Numata M., Hashimoto M., Hosoyama Y.,
RA Tsuchikane K., Noguchi M., Hirakata S., Ichikawa N., Ohji S., Yamazoe A.,
RA Fujita N.;
RT "Whole genome shotgun sequence of Vibrio ezurae NBRC 102218.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD81308.1}.
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DR EMBL; BATM01000055; GAD81308.1; -; Genomic_DNA.
DR RefSeq; WP_021715005.1; NZ_BATM01000055.1.
DR AlphaFoldDB; U3CU98; -.
DR STRING; 1219080.VEZ01S_55_00250; -.
DR eggNOG; COG0318; Bacteria.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000016562; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05936; FC-FACS_FadD_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF8; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:GAD81308.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016562}.
FT DOMAIN 29..419
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 470..544
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 560 AA; 62172 MW; 10AF72934BE71B52 CRC64;
MNKPWLSRYP SDVPETIDPD SYSSLIEMFE NSVQKFADQP AFTNMGSVMT YRKLEERSRA
FAAYLQNELK LKKGDRVALM MPNLLQYPIA LFGVLRAGCI AVNVNPLYTP RELEHQLNDA
QVETIVIVSN FANTLEQIVD NTSVKNVVLT SLGQMLPRAK GTVVDFVVKY VKGMVPKYDL
PGAISFRKAL YKGRRLQYVK PFLSGEDIAF LQYTGGTTGV AKGAVLTHRN MVANVLQAKG
AYLGKLEVGK ELVVTALPLY HIFALTVNGL LFLELGANNL LITNPRDIPT FVKELKKVPF
TAITGVNTLF NALVNNEDFH ELDFSHMHLS VGGGMAVQKV VADKWKKTTG VFLLEGYGLT
ECSPLVSGCP HDMSDYNGSI GLPVPSTEVR IVNDEGEVLP NTEVGELQVR GPQVMQGYWQ
RPEATREVIS QDGWLSTGDV VKFDEEGFLH IVDRKKDMIL VSGFNVYPNE IEDVVALHGK
VLEVAAIGEP HEVSGEVVKI CVVKRDPSLT KEELISHCRQ HLTGYKVPKI VTFMDDLPKT
NVGKILRREL RSETETEKSA
//
