ID U3CYS0_CALJA Unreviewed; 347 AA.
AC U3CYS0;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=ADAMTS like 3 {ECO:0000313|Ensembl:ENSCJAP00000087007.1};
DE SubName: Full=Endophilin-A3 {ECO:0000313|EMBL:JAB24732.1};
GN Name=SH3GL3 {ECO:0000313|EMBL:JAB24732.1};
GN Synonyms=ADAMTSL3 {ECO:0000313|Ensembl:ENSCJAP00000087007.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB24732.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000087007.1, ECO:0000313|Proteomes:UP000008225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB24732.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Cerebellum {ECO:0000313|EMBL:JAB44612.1}, and Cerebral cortex
RC {ECO:0000313|EMBL:JAB24732.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000087007.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the endophilin family.
CC {ECO:0000256|ARBA:ARBA00006697}.
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DR EMBL; GAMR01009200; JAB24732.1; -; mRNA.
DR EMBL; GAMP01008143; JAB44612.1; -; mRNA.
DR RefSeq; XP_002749231.1; XM_002749185.3.
DR Ensembl; ENSCJAT00000137381.1; ENSCJAP00000087007.1; ENSCJAG00000015699.5.
DR GeneID; 100399206; -.
DR KEGG; cjc:100399206; -.
DR CTD; 6457; -.
DR GeneTree; ENSGT00940000158143; -.
DR OrthoDB; 25371at2759; -.
DR TreeFam; TF313281; -.
DR Proteomes; UP000008225; Chromosome 6.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd07615; BAR_Endophilin_A3; 1.
DR CDD; cd11803; SH3_Endophilin_A; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR032469; Endophilin-A3_BAR.
DR InterPro; IPR035824; Endophilin_A_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF45; ENDOPHILIN-A3; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 18..249
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 285..344
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 251..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 347 AA; 39239 MW; 5F73848ACD794547 CRC64;
MSVAGLKKQF HKASQLFSEK ISGAEGTKLD DEFLDMERKI DVTNKAVAEI LSKTTEYLQP
NPAYRAKLGM LNTVSKIRGQ VKTTGYPQTE GLLGDCMLKY GKELGEDSTF GNALMEVGES
MKLMAEVKDS LDINVKQTFI DPLQLLQDKD LKEIGHHLKK LEGRRLDYDY KKKRVGKIPD
EEVRQAVEKF EESKELAERS MFNFLENDVE QVSQLAVFIE AALDYHKQST EILQELQSKL
QMRISAASSV PRREYKPRPV KRSSSEFNGV STTSVAKTTG SNVPMDQPCC RGLYDFEPEN
QGELGFKEGD IITLTNQIDE NWYEGMIHGE SGFFPINYVE VIVPLPQ
//
