ID U3EPJ6_CALJA Unreviewed; 507 AA.
AC U3EPJ6;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=TOM1-like protein 2 isoform 3 {ECO:0000313|EMBL:JAB46452.1};
DE SubName: Full=Target of myb1 like 2 membrane trafficking protein {ECO:0000313|Ensembl:ENSCJAP00000086282.1};
GN Name=TOM1L2 {ECO:0000313|EMBL:JAB46452.1,
GN ECO:0000313|Ensembl:ENSCJAP00000086282.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB46452.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000086282.1, ECO:0000313|Proteomes:UP000008225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB46452.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB09438.1}, Cerebellum
RC {ECO:0000313|EMBL:JAB46452.1}, Cerebral cortex
RC {ECO:0000313|EMBL:JAB30449.1}, Hippocampus
RC {ECO:0000313|EMBL:JAB23026.1}, and Skeletal muscle
RC {ECO:0000313|EMBL:JAB41335.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000086282.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TOM1 family. {ECO:0000256|ARBA:ARBA00007708,
CC ECO:0000256|PIRNR:PIRNR036948}.
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DR EMBL; GAMT01002423; JAB09438.1; -; mRNA.
DR EMBL; GAMS01000110; JAB23026.1; -; mRNA.
DR EMBL; GAMR01003483; JAB30449.1; -; mRNA.
DR EMBL; GAMQ01000516; JAB41335.1; -; mRNA.
DR EMBL; GAMP01006303; JAB46452.1; -; mRNA.
DR STRING; 9483.ENSCJAP00000052542; -.
DR Ensembl; ENSCJAT00000121466.1; ENSCJAP00000086282.1; ENSCJAG00000009003.5.
DR GeneTree; ENSGT00940000156940; -.
DR Proteomes; UP000008225; Chromosome 5.
DR Bgee; ENSCJAG00000009003; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR CDD; cd14238; GAT_TM1L2; 1.
DR CDD; cd16996; VHS_Tom1L2; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR014645; TOM1.
DR InterPro; IPR027429; TOM1L2_VHS_dom.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR13856:SF31; TOM1-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR13856; VHS DOMAIN CONTAINING PROTEIN FAMILY; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR PIRSF; PIRSF036948; TOM1; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 2: Evidence at transcript level;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR036948};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR036948}.
FT DOMAIN 20..152
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 219..307
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 162..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 507 AA; 55548 MW; D7FBD6AADED0D7C8 CRC64;
MEFLLGNPFS TPVGQCLEKA TDGSLQSEDW TLNMEICDII NETEEGPKDA IRALKKRLNG
NRNYREVMLA LTVLETCVKN CGHRFHILVA NRDFIDSVLV KIISPKNNPP TIVQDKVLTL
IQAWADAFRS SPDLTGVVHI YEELKRKGVE FPMADLDALS PIHTPQRSVP EVDPAATMPR
SQSQQRTSAG SYSSPPPAPY SAPQAPALSV TGPITASSEQ IARLRSELDV VRGNTKVMSE
MLTEMVPGQE DSSDLELLQE LNRTCRAMQQ RIVELISRVS NEEVTEELLH VNDDLNNVFL
RYERFERYRS GRSVQNASNG VLNEVTEDNL IDLGPGSPAV VSPMVGNTAP PSSLSSQLAG
LDLGTESVSG TLSSLQQCNP RDGFDMFSQT RGNSLAEQRK TVTYEDPQAV GGLASALDSR
KQSSEGIPVA QPSVMDDIEV WLRTDLKGDD LEEGVTSEEF DKFLEERAKA AEMVPDLPSP
PMEAPAPASN PSGRKKPERS EDALFAL
//
