ID U3GW57_9CORY Unreviewed; 232 AA.
AC U3GW57;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Cobalt transport protein CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
DE AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
DE Short=ECF transporter S component CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
GN Name=cbiM {ECO:0000256|HAMAP-Rule:MF_01462};
GN ORFNames=CARG_08315 {ECO:0000313|EMBL:AGU15770.1};
OS Corynebacterium argentoratense DSM 44202.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1348662 {ECO:0000313|EMBL:AGU15770.1, ECO:0000313|Proteomes:UP000016943};
RN [1] {ECO:0000313|EMBL:AGU15770.1, ECO:0000313|Proteomes:UP000016943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44202 {ECO:0000313|EMBL:AGU15770.1};
RX PubMed=24092787;
RA Bomholt C., Glaub A., Gravermann K., Albersmeier A., Brinkrolf K.,
RA Ruckert C., Tauch A.;
RT "Whole-Genome Sequence of the Clinical Strain Corynebacterium
RT argentoratense DSM 44202, Isolated from a Human Throat Specimen.";
RL Genome Announc. 1:e00793-13(2013).
CC -!- FUNCTION: Part of the energy-coupling factor (ECF) transporter complex
CC CbiMNOQ involved in cobalt import. {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- SUBUNIT: Forms an energy-coupling factor (ECF) transporter complex
CC composed of an ATP-binding protein (A component, CbiO), a transmembrane
CC protein (T component, CbiQ) and 2 possible substrate-capture proteins
CC (S components, CbiM and CbiN) of unknown stoichimetry.
CC {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01462};
CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01462}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CbiM family. {ECO:0000256|HAMAP-
CC Rule:MF_01462}.
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DR EMBL; CP006365; AGU15770.1; -; Genomic_DNA.
DR RefSeq; WP_021012163.1; NC_022198.1.
DR AlphaFoldDB; U3GW57; -.
DR STRING; 1348662.CARG_08315; -.
DR GeneID; 78250405; -.
DR KEGG; caz:CARG_08315; -.
DR PATRIC; fig|1348662.3.peg.1644; -.
DR eggNOG; COG0310; Bacteria.
DR HOGENOM; CLU_052508_3_0_11; -.
DR OrthoDB; 9809846at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000016943; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.1760.20; -; 1.
DR HAMAP; MF_01462; CbiM; 1.
DR InterPro; IPR018024; CbiM.
DR InterPro; IPR002751; CbiM/NikMN.
DR NCBIfam; TIGR00123; cbiM; 1.
DR PANTHER; PTHR43627; -; 1.
DR PANTHER; PTHR43627:SF1; COBALT TRANSPORT PROTEIN CBIM; 1.
DR Pfam; PF01891; CbiM; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Cobalt {ECO:0000256|ARBA:ARBA00023285, ECO:0000256|HAMAP-Rule:MF_01462};
KW Cobalt transport {ECO:0000256|ARBA:ARBA00022426, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01462};
KW Reference proteome {ECO:0000313|Proteomes:UP000016943};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01462}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 41..58
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 79..102
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 108..127
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 139..163
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 183..202
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
SQ SEQUENCE 232 AA; 24057 MW; 52E984FE4112926E CRC64;
MHIAEGFLPA MHCVGWAAAS APFVIHGAYA VNKQLKEKPE TGLLLGAAGA FSFVLSAIKM
PSVTGSSSHP TGTGLGAVLF KPPVMALLGG IVLLFQALLL AHGGLTTLGA NIFSMAIVGP
WVAYGVWRGM RGAHLPASWA IFFAAVLGDF STYCVTATQL ALAHHANGFW SAWSNFLLLY
APTQVPLALA EGIVTVLVFF AMRTTAARDL LTLGVLKKSE LTAATPAAAP AA
//
