ID   U3HYD3_ANAPP            Unreviewed;       386 AA.
AC   U3HYD3;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 2.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Divergent protein kinase domain 2A {ECO:0000313|Ensembl:ENSAPLP00000000003.2};
GN   Name=DIPK2A {ECO:0000313|Ensembl:ENSAPLP00000000003.2};
OS   Anas platyrhynchos platyrhynchos (Northern mallard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Anas.
OX   NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000000003.2, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Ensembl:ENSAPLP00000000003.2, ECO:0000313|Proteomes:UP000016666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT   "A new Pekin duck reference genome.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000000003.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the DIPK family.
CC       {ECO:0000256|ARBA:ARBA00006338}.
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DR   AlphaFoldDB; U3HYD3; -.
DR   STRING; 8840.ENSAPLP00000000003; -.
DR   Ensembl; ENSAPLT00000000570.2; ENSAPLP00000000003.2; ENSAPLG00000000595.2.
DR   GeneTree; ENSGT00520000055625; -.
DR   HOGENOM; CLU_052524_1_0_1; -.
DR   OMA; DICNHHL; -.
DR   Proteomes; UP000016666; Chromosome 9.
DR   GO; GO:0030126; C:COPI vesicle coat; IEA:Ensembl.
DR   GO; GO:0005615; C:extracellular space; IEA:Ensembl.
DR   GO; GO:0000139; C:Golgi membrane; IEA:Ensembl.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0034392; P:negative regulation of smooth muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0051896; P:regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; IEA:Ensembl.
DR   InterPro; IPR020519; DIPK2A/B.
DR   InterPro; IPR022049; FAM69_kinase_dom.
DR   PANTHER; PTHR32073:SF6; DIVERGENT PROTEIN KINASE DOMAIN 2A; 1.
DR   PANTHER; PTHR32073; GH11358P; 1.
DR   Pfam; PF12260; PIP49_C; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          206..370
FT                   /note="FAM69 protein-kinase"
FT                   /evidence="ECO:0000259|Pfam:PF12260"
SQ   SEQUENCE   386 AA;  44278 MW;  CA305618A46534AE CRC64;
     MLRLVSLKLG RLYRYVKLAV LGSLAAALVL NTHSLLASLQ RNELAERRFL QLNKCPACWG
     TSWCRKFLNG QLRLESWGRL RLLDFFNVKN VYFARYGEPR EGSRRVVLKR LGSAQELADI
     DAKICRRATG RGRCDLPQAL HATEFASLNG DVRLLTPDAV EGWSDLVHCP SQRLLDRLVR
     RYAETKDSGS FLLRNLKDSE RMQLLITLAF NPEPLVLQSF PSDEGWPFAK YLGACGRMVA
     VNYVGEELWS YFHAPWEKRV DLAWQLMEIA EQLTNNDFEF ALYLLDVSFD NFAVGPRDGK
     VIIVDAENVL VADKRLIRQN KPENWDVWYE SKFDDCDKEA CLSFSKEILC ARVTVDHNYY
     AICQNLLSRH ATWRGTSGGL LHDPPR
//