ID U3I038_ANAPP Unreviewed; 130 AA.
AC U3I038;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Cholecystokinin {ECO:0000313|Ensembl:ENSAPLP00000000608.1};
GN Name=CCK {ECO:0000313|Ensembl:ENSAPLP00000000608.1};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000000608.1, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000000608.1, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000000608.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU004362}.
CC -!- SIMILARITY: Belongs to the gastrin/cholecystokinin family.
CC {ECO:0000256|ARBA:ARBA00006273, ECO:0000256|RuleBase:RU004362}.
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DR AlphaFoldDB; U3I038; -.
DR STRING; 8840.ENSAPLP00000000608; -.
DR Ensembl; ENSAPLT00000001177.2; ENSAPLP00000000608.1; ENSAPLG00000001188.2.
DR GeneTree; ENSGT00390000003571; -.
DR OMA; YSGLCIC; -.
DR Proteomes; UP000016666; Chromosome 2.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro.
DR GO; GO:0051428; F:peptide hormone receptor binding; IEA:Ensembl.
DR GO; GO:0007586; P:digestion; IEA:InterPro.
DR InterPro; IPR015499; CCK-like.
DR InterPro; IPR001651; Gastrin/CCK.
DR InterPro; IPR013152; Gastrin/cholecystokinin_CS.
DR PANTHER; PTHR10786; CHOLECYSTOKININ; 1.
DR PANTHER; PTHR10786:SF0; CHOLECYSTOKININ; 1.
DR Pfam; PF00918; Gastrin; 1.
DR SMART; SM00029; GASTRIN; 1.
DR PROSITE; PS00259; GASTRIN; 1.
PE 3: Inferred from homology;
KW Amidation {ECO:0000256|ARBA:ARBA00022815};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..130
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019730270"
FT DOMAIN 3..130
FT /note="Gastrin/cholecystokinin peptide hormone"
FT /evidence="ECO:0000259|Pfam:PF00918"
SQ SEQUENCE 130 AA; 14330 MW; 6BB685968CED9317 CRC64;
MYSGICICVF LAVLSVSSFG QQTGGSHNDN FLAAELEQSL TEHHRHARAP LSTGPLKSAP
QLDGSLDQRA SIGALLAKYL QQARKGPTGR LSVMGNRVQS IDPTHRINDR DYMGWMDFGR
RSAEEYEYSS
//
