ID   U3I0A8_ANAPP            Unreviewed;       250 AA.
AC   U3I0A8;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 2.
DT   24-JAN-2024, entry version 48.
DE   SubName: Full=Interleukin 22 receptor subunit alpha 2 {ECO:0000313|Ensembl:ENSAPLP00000000678.2};
GN   Name=IL22RA2 {ECO:0000313|Ensembl:ENSAPLP00000000678.2};
OS   Anas platyrhynchos platyrhynchos (Northern mallard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Anas.
OX   NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000000678.2, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Ensembl:ENSAPLP00000000678.2, ECO:0000313|Proteomes:UP000016666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT   "A new Pekin duck reference genome.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000000678.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; U3I0A8; -.
DR   SMR; U3I0A8; -.
DR   STRING; 8840.ENSAPLP00000000678; -.
DR   Ensembl; ENSAPLT00000001249.2; ENSAPLP00000000678.2; ENSAPLG00000001211.2.
DR   GeneTree; ENSGT00940000161124; -.
DR   HOGENOM; CLU_081158_1_0_1; -.
DR   OMA; SMENYYE; -.
DR   Proteomes; UP000016666; Chromosome 3.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0042017; F:interleukin-22 binding; IEA:Ensembl.
DR   GO; GO:0042018; F:interleukin-22 receptor activity; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0042509; P:regulation of tyrosine phosphorylation of STAT protein; IEA:Ensembl.
DR   CDD; cd00063; FN3; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR   PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR   PANTHER; PTHR20859:SF51; INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-2; 1.
DR   Pfam; PF09294; Interfer-bind; 1.
DR   Pfam; PF01108; Tissue_fac; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 2.
DR   PROSITE; PS50853; FN3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..250
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5021448171"
FT   DOMAIN          47..142
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
SQ   SEQUENCE   250 AA;  28707 MW;  0CB4643B589E1A08 CRC64;
     MLFSHGAALL SMRGITFSSL FLLIHLLQDE ISSILVLESE DLQNSIKPQK VEFHSLNFNN
     TLHWQPGRAG EAKAAVYFVQ YKVYGQSTWQ NKEECWGIQD HFCDLTDETA DVQEPYYGRV
     RAASGGVYSD WSLSCRFTPW RETMIGPPTV NVVQSNKSII VKLQAPRSPY RRKRGSTIPM
     TNYYDLLYQV FIINNLLDER HRVLVYEGND KVVKIEDLRR GVSYCVVAKT YVPTLDRSSA
     YSSRQCTMLL
//