ID U3I2L4_ANAPP Unreviewed; 438 AA.
AC U3I2L4;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 2.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=Interferon gamma receptor 1 {ECO:0000313|Ensembl:ENSAPLP00000001484.2};
GN Name=IFNGR1 {ECO:0000313|Ensembl:ENSAPLP00000001484.2};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000001484.2, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000001484.2, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000001484.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; U3I2L4; -.
DR STRING; 8840.ENSAPLP00000001484; -.
DR Ensembl; ENSAPLT00000002058.2; ENSAPLP00000001484.2; ENSAPLG00000002012.2.
DR GeneTree; ENSGT00510000048929; -.
DR HOGENOM; CLU_043814_0_0_1; -.
DR OMA; NIMLPKS; -.
DR Proteomes; UP000016666; Chromosome 3.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0019955; F:cytokine binding; IEA:InterPro.
DR GO; GO:0004906; F:type II interferon receptor activity; IEA:Ensembl.
DR GO; GO:0038196; P:type III interferon-mediated signaling pathway; IEA:Ensembl.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR InterPro; IPR008355; Interferon_gamma_rcpt_asu.
DR PANTHER; PTHR20859:SF5; INTERFERON GAMMA RECEPTOR 1; 1.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR Pfam; PF09294; Interfer-bind; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR PRINTS; PR01777; INTERFERONGR.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..438
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019869526"
FT TRANSMEM 240..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..110
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF01108"
FT DOMAIN 124..229
FT /note="Interferon/interleukin receptor"
FT /evidence="ECO:0000259|Pfam:PF09294"
FT REGION 323..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..400
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 438 AA; 48769 MW; 35A295E371AA91D5 CRC64;
MRLLLALLPL LAAGRSAAGS GEQPPAVPSP TDLVVTSQNF KTVLSWQYQP MSETPYFVVE
MKPYIPGTYM TVSTCVNIST NSCDLSREVK ETFSPYWFRV KAVVGSEESE YVETNEFILQ
KHGKIGPPKL DLSRHADKII VDIYHPVFPM ELQPWITDNS DITYQVTFWD NETQHKNEVF
ADDCLQFTNK CSIDIPVTPN GSTYCVSAKG ILFQNLIVGA PSEESCIQVP LEQTTSTEKM
VIVCVAVVIM GVIFTLFCGF KKLREKNIKL PKSLVTVIRN LNTDNTFESK SEGKYISVVS
IMPVQSVSPL NSKETLLNIE PEEEAVSPEN FSEEASSCPL PETPDKVEES SVQKITEEVP
SDDEQNCKVK ESYFISSSNQ TDTSSNSSGP EISATEIHQT VMPRSCPKFS GYDKPHVPID
MLIDVGEEQR VIAYRPTD
//
