ID   U3I8N8_ANAPP            Unreviewed;      1397 AA.
AC   U3I8N8;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 2.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=Uveal autoantigen with coiled-coil domains and ankyrin repeats {ECO:0000313|Ensembl:ENSAPLP00000003609.2};
GN   Name=UACA {ECO:0000313|Ensembl:ENSAPLP00000003609.2};
OS   Anas platyrhynchos platyrhynchos (Northern mallard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Anas.
OX   NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000003609.2, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Ensembl:ENSAPLP00000003609.2, ECO:0000313|Proteomes:UP000016666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT   "A new Pekin duck reference genome.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000003609.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   Ensembl; ENSAPLT00000004212.2; ENSAPLP00000003609.2; ENSAPLG00000004038.2.
DR   GeneTree; ENSGT00940000157475; -.
DR   HOGENOM; CLU_005323_1_0_1; -.
DR   Proteomes; UP000016666; Chromosome 11.
DR   Gene3D; 1.10.287.1490; -; 1.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   PANTHER; PTHR24129; ANKYCORBIN; 1.
DR   PANTHER; PTHR24129:SF2; UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS; 1.
DR   Pfam; PF00023; Ank; 2.
DR   Pfam; PF12796; Ank_2; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 6.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 4.
DR   PROSITE; PS50088; ANK_REPEAT; 5.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          54..86
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          87..119
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          120..152
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          153..185
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          186..218
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   COILED          282..365
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          421..494
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          521..721
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          757..822
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          851..1067
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1092..1242
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1281..1364
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1397 AA;  159729 MW;  F38696E2035B65CC CRC64;
     MMTCWFSCAA KDTLNTDWNK YDDRLMKAAE RGDVEKVSSI LAKKGVCPTK LDVEGRSAFH
     VVASKGNLDC LNTILIHGVD ITATDAAGRN ALHLAAKYGH ALCLQKLLQY NCPTENVDLQ
     GRTALHDAAM SDCSSSIQLL CDHGASVNAK DGDGRTPLVL ATQMCRPTVC QLLIDRGADV
     NARDKQNRTA LMLGCEYGCK DAVEVLLKNG ADVSLVDGLG HDCAYYARIG DNIDILTLIK
     AAIEDSGKGR DTMKKGQSEQ KMSNMSQKWN RLHAQEEVNV RLYQKEHNAQ ELELENQDLK
     DRMREVQEEQ RMLLDRISGL QLQLNEEQMF ADDLEIEKDE LKKILATKEK QQEESLRTIE
     ALKAKLKYYE VDFVTSGSNF GNRKEDLLLK QGQVFAVESQ SRSMLRPLEL SLPNQSSSSE
     KETLKKELDN MRTCYGAAKE EINKLQRELS HKVSECKALA SECERTKEES DGQIKQLEDA
     LKDVQKRMFD SEGKVKQMQT HFLALKDHLT NEAASGNSKL TEELKDQLKE MKTKYEGASA
     EVGKLRNQIK QNELLVAEFK RDEGRLVEEN KRLQKELVKL EMERDKKGKN VMELEGQLKE
     TAAKLAHSVT SEKFENMKSL LSNEVNEKAR KLTEMEGEHE KLQAEIRLLK KESESQKAKL
     AQHIKPEDHE QMRSGFEQKS KELGKTISEL SQKNQALQKE LESFQVDNKM LKQQIQVLKT
     EIKSQNVPLK IHEELKKTSD VTVGDLTKKL FEITKKYNES KAEAEKLLVE KNNLSENISH
     FQAVYLSPEQ HKKEVEALKS SGIELERQLA ELQKKYDDEQ EKMCKLVSEN TVIRETLRDQ
     YVLATTHEEI KTVLNNTLEE TNRELSDLKE KTEEIKREFV RVNEENGTLK NKVNLLQNQL
     QTEYISLKDH EAKVTTLNKS MQELQENNAA IMAEYKRGQE EILQLHAEIE AQKKELDTIQ
     ECIKSRYAPV ASFEDREQSF EATVKELKAQ LQEQAQKCRE SEEENTKYKQ ENEKLKNGIL
     SIQNDLQQNY ILAEKSHELE KMFASKMEEL NEQLRELLQK YTGNKDEKGE LQESAKQNAP
     LQAPVEGQHL SVEQIEALKK ALGHTIEDLK EALRSKKECY DKETLKVGEL QQELLDLKKS
     SISLVEYTQM KEMLEQEIKA AKDSLKEKEG ENQVKNEEIQ KLQAEIQLNQ QALTDLESKE
     VIDMAEYKSM KSTLEAQINS IAEDLSCVNK KYEEACEEAL QAKKNELSLK DEKELLQLRS
     CSIEQEIKDQ KERCDKSLMT IIDLQKRIQE SAKQVEAKDN KITELLNDVE RLKQALNGLS
     QLTYTSGIPS KRQNQQVEML QNQVKTLQQQ LADAKRQHQE VVSVYRTHLL SAVQGHMDED
     VQAALLQIIR MRQGLVC
//