ID   U3IMP3_ANAPP            Unreviewed;       478 AA.
AC   U3IMP3;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 2.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Serine incorporator 3 {ECO:0000313|Ensembl:ENSAPLP00000008516.2};
GN   Name=SERINC3 {ECO:0000313|Ensembl:ENSAPLP00000008516.2};
OS   Anas platyrhynchos platyrhynchos (Northern mallard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Anas.
OX   NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000008516.2, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Ensembl:ENSAPLP00000008516.2, ECO:0000313|Proteomes:UP000016666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT   "A new Pekin duck reference genome.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000008516.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TDE1 family.
CC       {ECO:0000256|ARBA:ARBA00006665}.
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DR   AlphaFoldDB; U3IMP3; -.
DR   STRING; 8840.ENSAPLP00000008516; -.
DR   Ensembl; ENSAPLT00000009197.2; ENSAPLP00000008516.2; ENSAPLG00000008793.2.
DR   GeneTree; ENSGT01030000234623; -.
DR   OMA; GNPRVWY; -.
DR   Proteomes; UP000016666; Chromosome 21.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0009597; P:detection of virus; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IEA:Ensembl.
DR   GO; GO:1902237; P:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   InterPro; IPR005016; TDE1/TMS.
DR   PANTHER; PTHR10383; SERINE INCORPORATOR; 1.
DR   PANTHER; PTHR10383:SF51; SERINE INCORPORATOR 3; 1.
DR   Pfam; PF03348; Serinc; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        46..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        103..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        163..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        207..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        245..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        275..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        340..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        412..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        452..472
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   478 AA;  53198 MW;  703E8ACBD3933009 CRC64;
     MFLPMALPWG LGVLQNGSWV PCLCGGASCL LCRCCPSSSN STVTRLIYAF LLLLSTAVAC
     IMLAPGMEEQ LKKVPGFCDE GLHTLIPHLN GFVSCDVFVG YRAVYRISFA MAVFFFVLSL
     MMIAVKTSND PRAAVHNGFW FFKIAAIVGI MVGAFYIPEG PFTRAWFVVG IFGAFCFILI
     QLVLLVDFAH SWNENWVERM EEGNSKCWYA ALLSCTSLFY GLSLVFVVLF YVFYTKPEDC
     AENKFFISIN MILCIAVSIV SILPKVQEYQ PHSGLLQSSI ITLYTMYLTW SAMSNEPERN
     CNPSLLNIIT QIATPTVFPA NTTVVPATPA PPKSLQWWDA QSIVGLVIFV LCLLYSSIRS
     SSNSQVNKLM LSGSDSAILE EAGGAGSGAA EEGEVRRVVD NEKDGVQYSY TFFHFMLFLA
     SLYIMMTLTN WYSPDADFKT MTSKWPAVWV KITSSWLCLL LYLWTLVAPL VLTNRDFS
//