ID U3INL7_ANAPP Unreviewed; 275 AA.
AC U3INL7;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 2.
DT 24-JAN-2024, entry version 55.
DE SubName: Full=Metaxin 2 {ECO:0000313|Ensembl:ENSAPLP00000008840.2};
GN Name=MTX2 {ECO:0000313|Ensembl:ENSAPLP00000008840.2};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000008840.2, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000008840.2, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000008840.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004294}.
CC -!- SIMILARITY: Belongs to the metaxin family.
CC {ECO:0000256|ARBA:ARBA00009170}.
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DR AlphaFoldDB; U3INL7; -.
DR STRING; 8840.ENSAPLP00000008840; -.
DR Ensembl; ENSAPLT00000009525.2; ENSAPLP00000008840.2; ENSAPLG00000009123.2.
DR GeneTree; ENSGT00950000182919; -.
DR HOGENOM; CLU_044137_6_0_1; -.
DR OMA; YFQTRCL; -.
DR Proteomes; UP000016666; Chromosome 7.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0001401; C:SAM complex; IEA:Ensembl.
DR GO; GO:0006839; P:mitochondrial transport; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd03211; GST_C_Metaxin2; 1.
DR CDD; cd03079; GST_N_Metaxin2; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR040079; Glutathione_S-Trfase.
DR InterPro; IPR033468; Metaxin_GST.
DR InterPro; IPR019564; Sam37/metaxin_N.
DR PANTHER; PTHR12289; METAXIN RELATED; 1.
DR PANTHER; PTHR12289:SF38; METAXIN-2; 1.
DR Pfam; PF17171; GST_C_6; 1.
DR Pfam; PF10568; Tom37; 1.
DR SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR SFLD; SFLDG01180; SUF1; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 40..160
FT /note="Mitochondrial outer membrane transport complex
FT Sam37/metaxin N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10568"
FT DOMAIN 186..248
FT /note="Metaxin glutathione S-transferase"
FT /evidence="ECO:0000259|Pfam:PF17171"
FT REGION 256..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 275 AA; 31243 MW; 10023D5CB2332346 CRC64;
MMRSPNERLQ GPAAEPWPEN AALYQQLKED QILLSDNASS LAVQAFLQMC NLPVRVVCRA
NAEYMSPSGK VPFIHVGNQV VSELGPIVQF VKAKGHSLSD GLDEVQKAEM KAYMELVNNM
LLTAELYLQW CDDVTVEEIT HPRYGSPYPW PLNRILAYQK QWEIRRKMKA IGWAGKSLEQ
VLEDVDQCCQ ALSQRLGTQP YFFNKQPTEL DALVFGHLFT ILTTQLTTDE LSEKVKNYGN
LTAFCRRIEQ QYFEGHDKDN SGTAAPRSAK RSLLR
//
