ID   U3IWV0_ANAPP            Unreviewed;       943 AA.
AC   U3IWV0;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 2.
DT   27-MAR-2024, entry version 59.
DE   RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS   Anas platyrhynchos platyrhynchos (Northern mallard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Anas.
OX   NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000011726.2, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Proteomes:UP000016666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT   "A new Pekin duck reference genome.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000011726.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; U3IWV0; -.
DR   Ensembl; ENSAPLT00000012455.2; ENSAPLP00000011726.2; ENSAPLG00000011975.2.
DR   GeneTree; ENSGT00940000159725; -.
DR   HOGENOM; CLU_006480_3_2_1; -.
DR   OMA; ENTEYVM; -.
DR   Proteomes; UP000016666; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 9.
DR   Gene3D; 2.60.40.60; Cadherins; 9.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR013164; Cadherin_N.
DR   PANTHER; PTHR24028; CADHERIN-87A; 1.
DR   PANTHER; PTHR24028:SF234; PROTOCADHERIN GAMMA-A3; 1.
DR   Pfam; PF00028; Cadherin; 6.
DR   Pfam; PF08266; Cadherin_2; 2.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 7.
DR   SUPFAM; SSF49313; Cadherin-like; 9.
DR   PROSITE; PS00232; CADHERIN_1; 3.
DR   PROSITE; PS50268; CADHERIN_2; 7.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           31..943
FT                   /note="Cadherin domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5019743086"
FT   DOMAIN          74..134
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          135..243
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          244..348
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          349..453
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          454..664
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          665..773
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          774..878
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
SQ   SEQUENCE   943 AA;  103012 MW;  B27D49C7BBBABFB2 CRC64;
     MCTGTEGRWG RRKRALLCCV LVATWEAVWG QLRYSVPEEL PKGSFVGDVA KDLALQPATI
     RDRGARILDR GRTRYFALHA NSGHLVTAER LDREQLCEGV QRCVLRCEVI VEGEMKVYEI
     EVEITDINDN APTFGEAEKE MRMSEITAPG SRFSLSKAHD PDVGVNSLQS YELSGDEHFS
     LSVQAGADGE KRPELVLAKA LDREEAAFHE LVLRASDGGE PARTGTARIR VSVLDANDNA
     PVFSQAVYAV RVPEDVPVGS TLLTLTATDA DEGINANVKY SFKEISTKAS KVLDLDPETG
     LIRLVRSLDF EEGDSYEMEV QVQDGGGLFD TATISISVTD VNDNAPELTV SSALNEISED
     APPGTVVALL HVQDRDSGAN GEVRCSLVGD VPFRLRSSVG SYYSVVTSRE LDREEVSEYN
     VTVWASDGGS PSLRSSAVLA LRVLDVNDNA PVFAEARYSA RLPENNAEGA LVLTVRAWDA
     DWGQNARVRY RLAEGRVRGA PLSSYVSVQA ETGALYALRS FDYEEVREVE MCAAREGRWG
     RRQRALLCCV LVAAWEAAWG QLRYSVPEEL PKGSFVGDVA KDLALQLPAL RDRGARVVSA
     DRTQYFALHA NSGHLVTAER LDREQLCRLV ERCVLRCEVI VEGEMKVYSI EVEITDINDN
     APSFRESEPE LRISETTAPG SRFPLAEARD PDVGVNSLQS YELSGDEHFS LSVQAGADGE
     KRPELVLAKA LDREEAAFHE LVLRASDGGE PARTGTARIR VSVLDANDNA PVFSQAVYAV
     SVPEDVPVSS TLLTLTATDA DEGINANVKY SVKKATHLAS EIFYLDPETG SIRLVRSLDF
     EEGDSYDLQV MARDGGGLSD TATVSISVTD VNDYAPEISV RSALSEISED APPGTVVALL
     HVQDRDSGAN GEVRCSIEES VPFRLKRELD NYYSVVTSRE LDR
//