ID U3IXC1_ANAPP Unreviewed; 533 AA.
AC U3IXC1;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Adhesion G protein-coupled receptor G7 {ECO:0000313|Ensembl:ENSAPLP00000011897.2};
GN Name=ADGRG7 {ECO:0000313|Ensembl:ENSAPLP00000011897.2};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000011897.2, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000011897.2, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000011897.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; U3IXC1; -.
DR STRING; 8840.ENSAPLP00000011897; -.
DR Ensembl; ENSAPLT00000012629.2; ENSAPLP00000011897.2; ENSAPLG00000012118.2.
DR GeneTree; ENSGT00940000159169; -.
DR HOGENOM; CLU_370321_0_0_1; -.
DR OMA; MSFKINY; -.
DR Proteomes; UP000016666; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR47767; ADHESION G PROTEIN-COUPLED RECEPTOR G7; 1.
DR PANTHER; PTHR47767:SF1; ADHESION G-PROTEIN COUPLED RECEPTOR G7; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00303; GPS; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 161..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 158..459
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 533 AA; 60632 MW; F1DE68E862ED31EF CRC64;
MHPLLIFADE TAGNYQTTKL EIQKNATGLN DELSTEVQIL LNITRNSKRA GFVLYQNDKL
FQSKTYSSHS NFSKQIVSGN IDGGTASGVE IAFNPKYNTS KFLLHDYACV FWDYAVNDWN
TAGCTKEKGQ VLRCKCNHTT HFAVLMAFRI NYKYAKPLEC ISYVGVGLSI AGLVITILFQ
IFTRKTRKSS VTWMLVSLCS SMLTFNIIFI SGIENQNARN HSSNTSGSEQ QYSTYYTTNN
TLLKSDLVDP PADSWCMAVA VLLHYFLLAT FMWTALNCAQ LYLLLIRAMK PLPGNFIVTM
SAIGWERSFG IKKRFTVLFC FGILNNLSNI SFEMASLFMK SCWLAALDQD QNFSIKKPML
WSFLLPVALI LLFNIIIFIK IIVSVIWKEN KDLTRNKKDS FMGKITSTIS VVVVLGITWT
TGYFMLINQE ETSLVFSYVF CILNATQVKY LTILKLITEI MEKRCLIHLF RIFAQKRVLP
FWSVTHKTFP IIQISPGLYF KVTTEKTTLT GFSCTELQKI FPFPPSLIAI RNL
//
