ID U3IYL8_ANAPP Unreviewed; 480 AA.
AC U3IYL8;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 2.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=BAR/IMD domain containing adaptor protein 2 {ECO:0000313|Ensembl:ENSAPLP00000012344.2};
GN Name=BAIAP2 {ECO:0000313|Ensembl:ENSAPLP00000012344.2};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000012344.2, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000012344.2, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000012344.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, ruffle
CC {ECO:0000256|ARBA:ARBA00004466}.
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DR AlphaFoldDB; U3IYL8; -.
DR Ensembl; ENSAPLT00000013079.2; ENSAPLP00000012344.2; ENSAPLG00000012542.2.
DR GeneTree; ENSGT00940000153560; -.
DR HOGENOM; CLU_025877_0_1_1; -.
DR OMA; KNSYATX; -.
DR Proteomes; UP000016666; Chromosome 19.
DR GO; GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd11915; SH3_Irsp53; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR027681; IRSp53/IRTKS/Pinkbar.
DR InterPro; IPR035594; Irsp53_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14206; BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR14206:SF3; BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF08397; IMD; 2.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51338; IMD; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..59
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 107..194
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 320..383
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 262..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..405
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 480 AA; 52199 MW; 95CCE40DCE71C70F CRC64;
VSSGTIMEQF NPSLRNFISM GKTYEKALAS MTYAAKGYFD ALVKMGELAS ESQGSKELGK
SPAHGWMESV QGRLKAGDGT SSVLVGRRSW VSSLKGDENP ASVPDPDYIE AISNKQGELE
NYVSDGYKTA LTEERRRFCF LVEKQCAVAK SAITYHAKGK EMLTQKLPLW QQSCSDPNKI
PDRAIQLMQQ MAASSNGTIM PSPLSTSKSN LIISDPIPGA KPLPVPPELA PFVGRMSAQE
AMPVVNGASG TDSDDYSHWA EVKPAQPKSL SPPQPQKQLS DSYSNTLPVR KNVQPKNSYA
SAENKTLPRS SSMAAGLERN GRTRVQAIFS HAAGDNSTLL SFKEGDLITL LVPEARDGWH
YGESEKTKLR GWFPFSYTRV LDNDGSERVH TSLQQGKSSS TGNLLDKDDI AIPPPDYGMS
SQAFPSQNVN TFKQRPYSVA VPAFSQPLLN SALLSPCRNP FANVQLKPTV TNDRSAPLIS
//
