ID U3J014_ANAPP Unreviewed; 121 AA.
AC U3J014;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Vesicle associated membrane protein 1 {ECO:0000313|Ensembl:ENSAPLP00000012841.2};
GN Name=VAMP1 {ECO:0000313|Ensembl:ENSAPLP00000012841.2};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000012841.2, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000012841.2, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000012841.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic
CC vesicle membrane {ECO:0000256|ARBA:ARBA00004143}; Single-pass type IV
CC membrane protein {ECO:0000256|ARBA:ARBA00004143}. Membrane
CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004211}. Synapse, synaptosome
CC {ECO:0000256|ARBA:ARBA00034102}.
CC -!- SIMILARITY: Belongs to the synaptobrevin family.
CC {ECO:0000256|ARBA:ARBA00008025}.
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DR AlphaFoldDB; U3J014; -.
DR STRING; 8840.ENSAPLP00000012841; -.
DR Ensembl; ENSAPLT00000013586.2; ENSAPLP00000012841.2; ENSAPLG00000013048.2.
DR GeneTree; ENSGT00940000161390; -.
DR HOGENOM; CLU_064620_4_0_1; -.
DR OMA; IFCKYNV; -.
DR Proteomes; UP000016666; Chromosome 1.
DR GO; GO:0035579; C:specific granule membrane; IEA:Ensembl.
DR GO; GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0070821; C:tertiary granule membrane; IEA:Ensembl.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd15870; R-SNARE_VAMP2; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR InterPro; IPR001388; Synaptobrevin-like.
DR InterPro; IPR016444; Synaptobrevin/VAMP.
DR InterPro; IPR042855; V_SNARE_CC.
DR PANTHER; PTHR45701; SYNAPTOBREVIN FAMILY MEMBER; 1.
DR PANTHER; PTHR45701:SF1; VESICLE-ASSOCIATED MEMBRANE PROTEIN 1; 1.
DR Pfam; PF00957; Synaptobrevin; 1.
DR PIRSF; PIRSF005409; Synaptobrevin_euk; 1.
DR PRINTS; PR00219; SYNAPTOBREVN.
DR SUPFAM; SSF58038; SNARE fusion complex; 1.
DR PROSITE; PS00417; SYNAPTOBREVIN; 1.
DR PROSITE; PS50892; V_SNARE; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU00290};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 95..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..91
FT /note="V-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50892"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..22
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 121 AA; 13512 MW; AD6FE9FD00C23280 CRC64;
MSDPAQQPAP EGVPPAGGPP GSPPNLSSNR RLQQTQAQVE EVVDIMRVNV DKVLERDEKL
AELDDRADAL QAGASVFESS AAKLKRKYWW KNCKMMIMMG VICAIMVVVI VSKYRKNWDQ
R
//
