ID U3J2B3_ANAPP Unreviewed; 548 AA.
AC U3J2B3;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Serine/threonine kinase 38 {ECO:0000313|Ensembl:ENSAPLP00000013640.2};
GN Name=STK38 {ECO:0000313|Ensembl:ENSAPLP00000013640.2};
OS Anas platyrhynchos platyrhynchos (Northern mallard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000013640.2, ECO:0000313|Proteomes:UP000016666};
RN [1] {ECO:0000313|Ensembl:ENSAPLP00000013640.2, ECO:0000313|Proteomes:UP000016666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT "A new Pekin duck reference genome.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSAPLP00000013640.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; U3J2B3; -.
DR STRING; 8840.ENSAPLP00000013640; -.
DR Ensembl; ENSAPLT00000014402.2; ENSAPLP00000013640.2; ENSAPLG00000013800.2.
DR GeneTree; ENSGT00940000153544; -.
DR HOGENOM; CLU_000288_67_0_1; -.
DR OMA; CKDEMIR; -.
DR Proteomes; UP000016666; Chromosome 27.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000287; F:magnesium ion binding; IEA:Ensembl.
DR GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IEA:Ensembl.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:Ensembl.
DR CDD; cd21782; MobB_NDR1; 1.
DR CDD; cd05628; STKc_NDR1; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR InterPro; IPR000961; AGC-kinase_C.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR017892; Pkinase_C.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24356; SERINE/THREONINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR24356:SF221; SERINE_THREONINE-PROTEIN KINASE 38; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF00433; Pkinase_C; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51285; AGC_KINASE_CTER; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 172..465
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 466..538
FT /note="AGC-kinase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51285"
FT REGION 20..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..61
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 201
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 548 AA; 62717 MW; 16BC26F1A15E36C4 CRC64;
MRPALGAPGA RPVRVALRVG GPRWRSRGSA RSPGARGPFG PGPALRLRPA PSRPVPPRPA
VAVPTASCRR VQRLAAPFPG GSAMAMTGPT PCSSMSNHTK ERVTMTKVTL ENFYSNLIAQ
HEEREMRQKK LEQMMEEEGL KDEEKRIRRS AHAQKETEFL RLKRTRLGLE DFESLKVIGR
GAFGEVRLVQ KKDTGHVYAM KILRKADMLE KEQVGHIRAE RDILVEADSL WVVKMFYSFQ
DKLNLYLIME FLPGGDMMTL LMKKDTLTEE ETQFYIAETV LAIDSIHQLG FIHRDIKPDN
LLLDSKGHVK LSDFGLCTGL KKAHRTEFYR NLNHSLPSDF TFQNMNSKRK AETWKRNRRQ
LAFSTVGTPD YIAPEVFMQT GYNKLCDWWS LGVIMYEMLI GYPPFCSETP QETYKKVMNW
KETLTFPPEV PISDKAKDLI LRFCCEWEHR IGASGVEEIK SNPFFEGVDW EHIRERPAAI
SIEIKSIDDT SNFDEFPESD ILKPTVATIN HPDTDYKNKD WVFINYTYKR FEGLTARGAI
PSYMKTGK
//
