ID   U3J619_ANAPP            Unreviewed;       431 AA.
AC   U3J619;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 2.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=Lipase {ECO:0000256|PIRNR:PIRNR000862};
OS   Anas platyrhynchos platyrhynchos (Northern mallard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Anas.
OX   NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000014946.2, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Ensembl:ENSAPLP00000014946.2, ECO:0000313|Proteomes:UP000016666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT   "A new Pekin duck reference genome.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000014946.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|PIRNR:PIRNR000862}.
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DR   AlphaFoldDB; U3J619; -.
DR   STRING; 8840.ENSAPLP00000014946; -.
DR   Ensembl; ENSAPLT00000015733.2; ENSAPLP00000014946.2; ENSAPLG00000015088.2.
DR   GeneTree; ENSGT00940000156860; -.
DR   HOGENOM; CLU_010974_0_0_1; -.
DR   OMA; PEQFMNI; -.
DR   Proteomes; UP000016666; Chromosome 6.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR025483; Lipase_euk.
DR   PANTHER; PTHR11005:SF157; LIPASE; 1.
DR   PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR000862};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963,
KW   ECO:0000256|PIRNR:PIRNR000862};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          114..412
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
SQ   SEQUENCE   431 AA;  48982 MW;  0C1AA727F57842E5 CRC64;
     MPRSNADIAR HHRTVWVSAS SSWPAHTSPI IPQSGEMWLL LLVALGLAQG LHGAALHGRV
     SRNNPEQFMN ISQKIRFQGY PSEEYDVLTD DGYFLSVNRI PHGKGDAGDS GSRPPVLIVH
     GFSLDGGDWV DNLPNSSLGF ILADAGYDVW IGNCRGNSWS QRHLNLSVQQ EEFWDFSFHE
     MAMYDVPAMV SFILQHTAQE KLYYVGHAQG NSLGFIAFSS MPQLAQKIKV FFALAPLYTF
     HHAKGPVLKI AFLPDIVLKT IFGTKQLTLV GREERAILAK TCSNMLTAEV CENEIFLIGG
     YNKKNLNTSR LDVYLAHFPD YTSVKTLLHW GQTAKTGDFK QFDYREKNQE KYNQTTPPFY
     RIEDMTVPTA LWSGGEDWVN PPVETQRLLP RITNIIHHEH FTDWNHFDHH WGQDAPQRMY
     RQIVALMEKN P
//