ID   U3J629_ANAPP            Unreviewed;       755 AA.
AC   U3J629;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 2.
DT   24-JAN-2024, entry version 56.
DE   SubName: Full=MTSS I-BAR domain containing 1 {ECO:0000313|Ensembl:ENSAPLP00000014956.2};
GN   Name=MTSS1 {ECO:0000313|Ensembl:ENSAPLP00000014956.2};
OS   Anas platyrhynchos platyrhynchos (Northern mallard).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Anas.
OX   NCBI_TaxID=8840 {ECO:0000313|Ensembl:ENSAPLP00000014956.2, ECO:0000313|Proteomes:UP000016666};
RN   [1] {ECO:0000313|Ensembl:ENSAPLP00000014956.2, ECO:0000313|Proteomes:UP000016666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hou Z.-C., Zhou Z.-K., Zhu F., Hou S.-S.;
RT   "A new Pekin duck reference genome.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAPLP00000014956.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; U3J629; -.
DR   Ensembl; ENSAPLT00000015743.2; ENSAPLP00000014956.2; ENSAPLG00000015070.2.
DR   GeneTree; ENSGT00950000183156; -.
DR   HOGENOM; CLU_004805_2_1_1; -.
DR   Proteomes; UP000016666; Chromosome 2.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR   CDD; cd07643; I-BAR_IMD_MIM; 1.
DR   CDD; cd22060; WH2_MTSS1; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR013606; I-BAR_dom.
DR   InterPro; IPR030127; MTSS1/MTSS2.
DR   InterPro; IPR003124; WH2_dom.
DR   PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR   PANTHER; PTHR15708:SF10; PROTEIN MTSS 1; 1.
DR   Pfam; PF08397; IMD; 1.
DR   Pfam; PF02205; WH2; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51338; IMD; 1.
DR   PROSITE; PS51082; WH2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016666}.
FT   DOMAIN          1..254
FT                   /note="IMD"
FT                   /evidence="ECO:0000259|PROSITE:PS51338"
FT   DOMAIN          727..744
FT                   /note="WH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51082"
FT   REGION          259..350
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          432..514
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          592..611
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          616..729
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          736..755
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        259..338
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        488..514
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        658..684
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   755 AA;  81899 MW;  498F877311250B7D CRC64;
     MEAVIEKECS ALGGLFQTII SDMKGSYPVW EDFINKAGKL QSQLRTTVVA AAAFLDAFQK
     VADMATNTRG GTREIGSALT RMCMRHRSIE SKLRQFSSAL IDCLINPLQE QMEEWKKVAN
     QLDKDHAKEY KKARQEIKKK SSDTLKLQKK AKKAEALGRG DIQPQLDSAL QDVNDKYLLL
     EETEKQAVRK ALIEERGRFC TFISMLRPVI EEEISMLGEI THLQTISDDL KSLTMDPHKL
     PSSSEQVILD LKGSDYSWSY QTPPSSPSTT MSRKSSVCSS LNSVNSSDSR SSGSHSHSPS
     SHYRYRSSNL PQQAPMRLSS VSSHDSGFMS QDAFQSKSPS PMPPEAPNQL SNGFYHCSLS
     SDPSVASVGA GPFPHFPPVS RAWTRAPSAL LPDYVHYYTI GPGMLPSSKI PSWKDWAKPG
     PYDQPVVNTL QRRKEKREPE LNGGAQSGPP APAEEAQRPR SMTVSTATRQ GEEMESCEEL
     ALALTRGLQL DTQRSSRDSL QCSSGYSTQT TTPCCSEDTI PSQVSDYDYF SVSGDQEAEQ
     QEFDKSSTIP RNSDISQSYR RMFQTKRPAS TAGLPTTLGP VIVTPGVATI RRTPSTKPSV
     RRGTIGAGPI PIKTPVIPVK TPTVPDIPGG LPGTLAGTEE CPEQSLESPA AGDGGQGVGS
     MPSSSWSGQA SVNPPPSSLK LSAADEQRQA VLEGEGEESE RDGGSTLAPG GQLELDPGDL
     SPGDVPQGED MLNAIRRGVK LKKTTTNDRS APRIS
//