ID U3JEH6_FICAL Unreviewed; 694 AA.
AC U3JEH6;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE SubName: Full=Scm polycomb group protein homolog 1 {ECO:0000313|Ensembl:ENSFALP00000001180.1};
GN Name=SCMH1 {ECO:0000313|Ensembl:ENSFALP00000001180.1};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000001180.1, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000001180.1, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000001180.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SCM family. {ECO:0000256|ARBA:ARBA00008469}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_005058409.1; XM_005058352.2.
DR AlphaFoldDB; U3JEH6; -.
DR STRING; 59894.ENSFALP00000001180; -.
DR Ensembl; ENSFALT00000001186.2; ENSFALP00000001180.1; ENSFALG00000001135.2.
DR GeneID; 101820501; -.
DR KEGG; fab:101820501; -.
DR CTD; 22955; -.
DR eggNOG; KOG3766; Eukaryota.
DR GeneTree; ENSGT00940000157999; -.
DR HOGENOM; CLU_015000_1_1_1; -.
DR OMA; NKEFCSM; -.
DR OrthoDB; 2908161at2759; -.
DR Proteomes; UP000016665; Chromosome 23.
DR GO; GO:0010369; C:chromocenter; IEA:Ensembl.
DR GO; GO:0001673; C:male germ cell nucleus; IEA:Ensembl.
DR GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR CDD; cd20105; MBT_SCMH1_rpt1; 1.
DR CDD; cd20108; MBT_SCMH1_rpt2; 1.
DR CDD; cd09578; SAM_Scm; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.90.1150.190; SLED domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR047279; MBT_SCMH1_rpt1.
DR InterPro; IPR047280; MBT_SCMH1_rpt2.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR047531; SAM_Scm-like.
DR InterPro; IPR033763; SCML2_RBR.
DR InterPro; IPR021987; SLED.
DR InterPro; IPR038348; SLED_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF68; POLYCOMB PROTEIN SCMH1; 1.
DR Pfam; PF02820; MBT; 2.
DR Pfam; PF17208; RBR; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF12140; SLED; 1.
DR SMART; SM00561; MBT; 2.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS51079; MBT; 2.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT REPEAT 34..132
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 140..241
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT DOMAIN 627..692
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 470..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..278
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..293
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..521
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..575
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 585..625
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 694 AA; 77207 MW; 7665AAB228B4E7A7 CRC64;
MRKPGPQKAI DWKDGKKHKH SRPSESPSQY QGHFTWEKYL KETCAIPAPA HCFKQSYTPP
ANEFKISMKL EAQDPRNTTS TCIASVVGLT GARLRLRLDG SDNKNDFWRL VDSAEIQPIG
NCEKNGGMLQ PPLGFRLNAS SWPMFLLKTL NGAEMAPVRI FHKEPPSPSQ NFFKTGMKLE
AVDRKNPHFI CPATIGEVRG SEVLITFDGW RGAFDYWCRY DSRDIFPVGW CSLTGDNLQP
PGTKVVIPKS PLPASEVNSE KPSMHSSTKA GLGQQQGQRR RKTGKKRGRT TKALIHHPMP
TPSKSVEPLK FPRKRGPKPG SKRKPRTLLN PAPTSPTTST PEPDTSTVPQ DAATIPSSAM
QAPTVCIYLN KNGSTGPHLD KKKVQQLPDH FGPARASVVL QQAVQACIDC AYHQKTVFSF
LKQGHGGEVI SAVFDREQHT LNLPAVNSIT YVLRFLEKLC HNLRSDNLFG SQPFTQSSPM
QRSHQYDHDR YLPDRSSSLE GSLQGPGRGT KRFSQDSPPY TAPLSPKLPK NDRHPLEGET
FVLGDGLPGP LEPRLDPMDS ALNSVSSSSH SRSSRDYRLP GYRHLQQPSS LSQGSTSALR
RLSSGGSDRY LSSRDSPRLS SRDPSSWTVE EVMQFIRESD PQLGPHADLF RKHEIDGKAL
LLLRSDMMMK YMGLKLGPAL KLTYHIDKLK QGKF
//
