ID U3JG80_FICAL Unreviewed; 462 AA.
AC U3JG80;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Divergent protein kinase domain 1A {ECO:0000313|Ensembl:ENSFALP00000001784.2};
GN Name=DIPK1A {ECO:0000313|Ensembl:ENSFALP00000001784.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000001784.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000001784.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000001784.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004648}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the DIPK family.
CC {ECO:0000256|ARBA:ARBA00006338}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; U3JG80; -.
DR Ensembl; ENSFALT00000001793.2; ENSFALP00000001784.2; ENSFALG00000001706.2.
DR eggNOG; ENOG502QU5P; Eukaryota.
DR GeneTree; ENSGT00390000006452; -.
DR HOGENOM; CLU_039177_0_0_1; -.
DR Proteomes; UP000016665; Chromosome 8.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR022049; FAM69_kinase_dom.
DR InterPro; IPR029244; FAM69_N.
DR PANTHER; PTHR21093:SF4; DIVERGENT PROTEIN KINASE DOMAIN 1A; 1.
DR PANTHER; PTHR21093; UNCHARACTERIZED; 1.
DR Pfam; PF12260; PIP49_C; 1.
DR Pfam; PF14875; PIP49_N; 1.
DR SMART; SM01299; PIP49_N; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 62..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..211
FT /note="FAM69 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01299"
SQ SEQUENCE 462 AA; 52925 MW; 50BDE614FC7E6597 CRC64;
MAELGRLDGE FKIPICLLVK LAEFSKPSET KEAPFQSRRC VIPTHPIHLL DQVRLSYVRI
KYLFISWLVV FIGSWIMYVQ YSTYTELCRG HDCRKIICDK YKTGVIDGSA CSSLCAKETL
YFGKCLSTKP NNQIYLGIWG NLQSVIKCQM EEAAQLDFGT DPEPRKEIVL FDKPTKGTTV
EKFKEMVYGL FKAKLGEQGN LSELVNLILS FADGNKDGRV SLPEAKSAWA LLQLEEFLLM
VILQDKEHTP KLIGFCGDLY VTERVEYTSL YGISLPWIIE LLIPSGFRRS MDQWFTPSWP
RKAKIAIGLL EFVEDIFHGP YGNFLMCDTS AKNLGYNDKY DLKMMDMRKI VPEINLKEII
KDRQCDSDLD CIYGTDCRTL CDQSKMRCTT EVIQPNLAKA CQLLKDYLLR GAPSDIHEEL
EKQLYLCIAL KVTANQMEME HSLILNNLKT LLWKKISHTN DS
//
