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Database: UniProt
Entry: U3JHJ1_FICAL
LinkDB: U3JHJ1_FICAL
Original site: U3JHJ1_FICAL 
ID   U3JHJ1_FICAL            Unreviewed;       485 AA.
AC   U3JHJ1;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   26-FEB-2020, entry version 43.
DE   SubName: Full=Lysophosphatidylcholine acyltransferase 1 {ECO:0000313|Ensembl:ENSFALP00000002245};
GN   Name=LPCAT1 {ECO:0000313|Ensembl:ENSFALP00000002245};
OS   Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX   NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000002245, ECO:0000313|Proteomes:UP000016665};
RN   [1] {ECO:0000313|Ensembl:ENSFALP00000002245}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2013) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
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DR   EMBL; AGTO01001914; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_005041818.1; XM_005041761.2.
DR   STRING; 59894.ENSFALP00000002245; -.
DR   Ensembl; ENSFALT00000002257; ENSFALP00000002245; ENSFALG00000002161.
DR   GeneID; 101820727; -.
DR   KEGG; fab:101820727; -.
DR   CTD; 79888; -.
DR   GeneTree; ENSGT00950000182744; -.
DR   HOGENOM; CLU_025017_0_1_1; -.
DR   KO; K13510; -.
DR   OMA; GAFEILW; -.
DR   OrthoDB; 1266853at2759; -.
DR   Proteomes; UP000016665; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005811; C:lipid droplet; IEA:Ensembl.
DR   GO; GO:0047184; F:1-acylglycerophosphocholine O-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0047159; F:1-alkenylglycerophosphocholine O-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0047191; F:1-alkylglycerophosphocholine O-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:2001246; P:negative regulation of phosphatidylcholine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; IEA:Ensembl.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0043129; P:surfactant homeostasis; IEA:Ensembl.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR   Pfam; PF01553; Acyltransferase; 1.
DR   SMART; SM00563; PlsC; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          331..366
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          402..437
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          454..485
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        454..469
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        471..485
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   485 AA;  54941 MW;  10F739F1456FDACD CRC64;
     MTLTLFPIRL FFAAFMMLLA WPFAFIASMG SDEQELEKPL SWWRKIVDIL LKAIMRMMWL
     AGGFHWINVK GRRALPAEAA ILTVAPHSSY FDAIPVTMTF ASIVMKAESK DIPVWGTLIK
     YIRPVFVSRS DQDSRRKTVE EIKRRAQSNG KWPQIMIFPE GTCTNRSCLI TFKPGAFIPG
     VPVQPVVLRY PNKLDTITWT WQGPGAFEIL WLTLCQFHNS VEIEFLPVYT PSEEERKNPV
     LYANNVRRVM AEALGVSVTD YTFEDCQLAL AEGQLRLPSD TCLLEFAKLV RSLGLKPETL
     EDDLDKYAAS VMKMKKEKVD LKEFSAYLEF PVSQTLESMF ALFDEKEDGV IDIREFVIAL
     SVVCKPSKTL ETIQLAFQLY QSEGGTVTEE DLACILKTAM GVSQIDVTHL FRAVDEEEKG
     KITYDDFYTF AVLHPHFAEE YLYADQMGAE SGLETSSLSA PNGICTDFSP DSSGDRRKPL
     QKKLN
//
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